ArticleJournal of perinatology : official journal of the California Perinatal Association2025
The number of blood transfusions received and the incidence and severity of chronic lung disease among NICU patients born >31 weeks gestation.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Assessment of iron sufficiency in premature infants treated with darbepoetin using conventional and novel erythrocyte metrics.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Redefining neonatal thrombocytopenia: an evidence-based approach, improved by the refineR algorithm.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Decreasing packed red blood cell (pRBC) transfusions in neonates through quality improvement.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Designing and implementing a clinical decision support tool to improve compliance with NICU transfusions.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- The risk of developing severe bronchopulmonary dysplasia: evaluating associations with the nucleated red blood cell count at birth and volume of transfusions received.Frontiers in pediatrics · 2026Article
- Three studies needed to inform the design of the U-BET (umbilical cord blood for extremely low-gestational-age transfusions) clinical trial.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Cord red blood cell transfusions for severe retinopathy in preterm neonates in Italy: a multicenter randomized controlled trial.EClinicalMedicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe previously reported the possible pathogenic role, among infants born ≤29 weeks, of transfusions in bronchopulmonary dysplasia. The present study examined this association in infants born >31 weeks. STUDY
designAnalysis of red blood cell (RBC) and platelet transfusions in five NICUs to infants born >31 weeks, and chronic neonatal lung disease (CNLD) at six-weeks of age.
resultsSeven-hundred-fifty-one infants born >31 weeks were still in the NICU when six-weeks of age. CNLD was identified in 397 (53%). RBC and platelet transfusions were independently associated with CNLD after controlling for potential confounders. For every transfusion, the adjusted odds of developing CNLD increased by a factor of 1.64 (95% CI, 1.38-2.02; p < 0.001).
conclusionsAmong NICU patients born >31 weeks, transfusions received by six weeks are associated with CNLD incidence and severity. Though we controlled for known confounding variables in our regression models, severity of illness is an important confounder that limits our conclusions.
Indexed as
Identifiers
39402132What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.