Evidence map›Paper›PMID 39402078›Full record

ArticleScientific reports2024

Nrf-2/HO-1 activation protects against oxidative stress and inflammation induced by metal welding fume UFPs in 16HBE cells.

Mengchao Ying, Yun Yang, Qian Huo, Jingqiu Sun, Xinyu Hong, Feng Yang, Yamin Fang, Lingyi Lu, Tingfeng Mao, Ping Xiao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mengchao YingShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Yun YangShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Qian HuoShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Jingqiu SunShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Xinyu HongShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Feng YangShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Yamin FangShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China.
Lingyi LuXuhui District Center for Disease Control and Prevention, Shanghai, 200237, China.
Tingfeng MaoXuhui District Center for Disease Control and Prevention, Shanghai, 200237, China.
Ping XiaoShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China. xiaoping@scdc.sh.cn.
Gonghua TaoShanghai Municipal Center for Disease Control & Prevention, Shanghai, 200336, China. taogonghua@scdc.sh.cn.

Funding

Shanghai Municipal Health Commission 202140489Shanghai Sailing Program 21YF1439100Special fund of State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants SEPKL-EHIAEC-202204Three-year action plan of Shanghai Public Health System Construction GWVI-11.1-41Three-year action plan of Shanghai Public Health System Construction GWVI-11.2-YQ34
6 · The paper itself

Abstract

As one of the main occupational hazards, welding fumes can cause oxidative damage and induce series of diseases, such as COPD or asthma. To clarify the effects of the metal fume ultrafine particulates (MF-UFPs) of welding fumes on oxidative damage, UFPs were collected by melt inert gas (MIG) and manual metal arc (MMA) welding, and the composition was confirmed. Human bronchial epithelial 16HBE cells were treated with 0-1000 µg/cm

Indexed as

Heme Oxygenase-1InflammationNF-E2-Related Factor 2Oxidative StressParticulate MatterWeldingCell LineCell SurvivalEpithelial CellsHumansMembrane Potential, MitochondrialMetalsReactive Oxygen SpeciesSignal TransductionHeme Oxygenase-1HMOX1 protein, humanMetalsNFE2L2 protein, humanNF-E2-Related Factor 2Particulate MatterReactive Oxygen SpeciesNrf-2/AREOxidative stressUltrafine particlesWelding fume

Identifiers

PMID39402078
PMCPMC11473639

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.