SynthesisInternational wound journal2024
Biodegradable Temporising matrix in the reconstruction of complex wounds: A systematic review and meta-analysis.
Synthesis in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biodegradable Temporising matrix in the reconstruction of complex wounds: A systematic review and meta-analysis.International wound journal · 2024Pooled it
- NovoSorb™ biodegradable temporizing matrix for post-excision wound reconstruction in a paediatric giant congenital melanocytic naevus: a case report.Journal of surgical case reports · 2026Article
- The Unknown Benefits of Dermal Matrices in Prevent Loss of Albumin in Patient with Major Burns.European burn journal · 2026Article
- Article
- Defining dermal matrices: Results of a global Delphi panel in surgical reconstruction.JPRAS open · 2026Article
- The Role and Efficacy of NovoSorb Biodegradable Temporizing Matrix in Complex Reconstructive Wounds: A Systematic Review.Plastic and reconstructive surgery. Global open · 2026Article
- Safety and efficacy of bio-engineered, autologous dermo-epidermal skin grafts in adolescent and adult burn patients: 1-year results of a prospective, randomized, controlled, multicenter phase IIB clinical trial.EClinicalMedicine · 2025Article
- Use of NovoSorb Biodegradable Temporizing Matrix for Reconstruction of Scrotal Fournier Gangrene Wound.Plastic and reconstructive surgery. Global open · 2025Article
- A case series to evaluate burn therapy practices after application of Biodegradable Temporising Matrix (BTM).Scars, burns & healingArticle
- NovoSorb® Biodegradable Temporising Matrix (BTM) for reconstruction of paediatric acute ischaemic limb injuries secondary to sepsis: A literature review and case series.Scars, burns & healingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the efficacy of biodegradable temporising matrix (BTM) in complex wound reconstruction.
methodsThe authors conducted a systematic review and meta-analysis as per the preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines following a literature search assessing BTM in complex wound reconstruction. The primary outcome measures included the proportion of BTM integration as well as integration time. Secondary outcomes included graft take over BTM, infection rate and other complications as well as scar outcome.
resultsTwenty six studies met the inclusion criteria with a total of 1153 complex wounds. The mean proportional integration was 92.7% at (95% confidence intervals [CI] 88.57, 96.87, p < 0.001) with a mean integration time of 34.05 days (95% CI 33.33, 34.79, p < 0.001). The infection rate was low at 12.6% with an untransformed proportion metric assessment (0.126, 0.08-0.168, p < 0.001) at the site of BTM application. Favourable scar outcomes were reported using the matching assessment using photographs with scars (MAPS) and patient and observer scar assessment scales (POSAS).
conclusionBTM offers a robust dermal template in reconstruction of complex wounds. The authors recommend for randomised controlled trials to enhance the current evidence base.
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