ArticleBMJ paediatrics open2024
Comparing qualitative and quantitative echocardiographic markers to assess cardiac contractility in newborn infants: protocol for a prospective cohort study.
Article in BMJ paediatrics open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNeonatologist-performed echocardiography (NPE) is increasingly used in the neonatal intensive care unit, aiding clinicians in enhancing diagnostic precision and guiding treatment decisions based on underlying pathophysiology. Experienced NPE operators typically use visual estimation of the cardiac contractility and if required confirm findings using quantitative echocardiographic markers.While various quantitative echocardiographic markers are available to assess left and right ventricular contractility, this study aims to compare the proficiency of NPE-experienced and non-experienced providers in accurately assessing cardiac contractility using a combination of commonly used qualitative and quantitative echocardiographic markers. METHODS AND ANALYSIS: Newborn infants, both inborn and outborn, undergoing routine NPE by the authors at Homerton University Hospital and Aberdeen Maternity Hospital from 1 April 2024 to 1 October 2024 will be studied. Indications for NPE include murmur evaluation, infants receiving intensive care and the need to assess underlying cardiovascular physiology.Blinded experienced and non-experienced NPE operators will independently assess left and right ventricular contractility using qualitative echocardiographic markers. The results will be compared with standard quantitative echocardiographic markers for cardiac contractility, and reliability studies will also be conducted for quantitative makers.Clinical data will be sourced from electronic patient records and national neonatal database. Sensitivity, specificity, positive predictive and negative predictive values, and positive and negative likelihood ratios will be calculated. ETHICS AND DISSEMINATION: The study is approved by the Health and Care Research Wales Research Ethics Committee and the Health Research Authority (HRA) (reference 23/HRA/3066). The study findings will be presented at national/international conferences and published in peer-reviewed scientific journals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.