Evidence map›Paper›PMID 39401466›Full record

ArticleJournal of neurosurgery. Case lessons2024

Hemorrhagic intramedullary spinal cord metastasis from renal cell carcinoma: a rare case 15 years after cured renal cell carcinoma. Illustrative case.

Mohammad Khalil Al-Barbarawi, Amr Badary, Jörg Silbermann, Oday Atallah, Mohamad Kinan Sultan, Adel Osman, Abdulaziz Albardan, Salah Maksoud, Wahab Moustafa

Abstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad Khalil Al-BarbarawiDepartment of Neurosurgery, Dessau Clinical Center, Academic Hospital of Brandenburg University, Dessau, Germany.
Amr BadaryDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Jörg SilbermannDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Oday AtallahDepartment of Neurosurgery, Hannover Medical School, Hannover University, Hannover, Germany.
Mohamad Kinan SultanDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Adel OsmanDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Abdulaziz AlbardanDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Salah MaksoudDepartment of Neurosurgery, Darmstadt Clinical Center, Darmstadt, Germany.
Wahab MoustafaDepartment of Neurotraumatology and Spine, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal cell carcinoma (RCC), the most common kidney cancer, often metastasizes to bones, lungs, liver, and the central nervous system. Intramedullary spinal metastasis from RCC is rare but can cause significant neurological deficits, necessitating prompt diagnosis and treatment through surgical intervention, radiotherapy, and immunotherapy. OBSERVATIONS: An 86-year-old man presented with progressive right lower-limb weakness and reduced sensation over 3 weeks. His medical history included a right nephrectomy for RCC 15 years earlier and L4-S1 spondylosis. Imaging identified a bleeding lesion in the conus medullaris at T11-12 and an incidental left kidney mass. Urgent surgical exploration led to a T12 laminectomy and en bloc removal of the lesion, which was confirmed as RCC metastasis. Postoperatively, the patient received focused radiotherapy and immunotherapy, showing significant motor and sensory improvement before dying 3 months later. LESSONS: This case underscores the importance of comprehensive diagnostic imaging for the accurate identification and characterization of spinal lesions. An interdisciplinary approach involving neurosurgeons, oncologists, radiologists, and pathologists is crucial for optimal treatment planning. Urgent surgical intervention can effectively address acute neurological deficits caused by intramedullary lesions. Additionally, adhering to postoperative care instructions, such as deep venous thrombosis prophylaxis, is vital to prevent fatal complications. https://thejns.org/doi/10.3171/CASE24349.

Indexed as

case reportconus medullarishemorrhagic metastasisintramedullary spinal cord metastasislate recurrencerenal cell carcinoma

Identifiers

PMID39401466
PMCPMC11488368

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.