Evidence map›Paper›PMID 39401086›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Circadian Clock Disruption and Growth of Kidney Cysts in Autosomal Dominant Polycystic Kidney Disease.

Abeda Jamadar, Christopher J Ward, Viji Remadevi, Meekha M Varghese, Navjot S Pabla, Michelle L Gumz, Reena Rao

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2026
    Article
  4. Review
  5. Review
  6. Polycystic Kidney Disease: A Disorder Out of Time?Journal of the American Society of Nephrology : JASN · 2025
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Abeda JamadarKidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
Christopher J WardKidney Institute, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0002-2507-9398
Viji RemadeviKidney Institute, University of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0003-1159-3262
Meekha M VargheseKidney Institute, University of Kansas Medical Center, Kansas City, Kansas.
Navjot S PablaDivision of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.ORCID 0000-0001-9408-0539
Michelle L GumzDivision of Nephrology, Hypertension, and Renal Transplantation, Department of Physiology and Aging, Department of Medicine, University of Florida, Gainesville, Florida.ORCID 0000-0002-1342-0878
Reena RaoKidney Institute, University of Kansas Medical Center, Kansas City, Kansas.

Funding

Polycystin Function Resource Development CoreU54DK126126 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Alan S Yu · 2020 to 2026
$5.8M
Pathogenic reciprocal interplay between cyst epithelium and myofibroblasts in polycystic kidney diseaseR01DK135308 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Reena Rao · 2023 to 2026
$1.9M
Spinning-Disk Confocal Microscope for Wide-Field, Super-Resolution, and Live-Cell ImagingS10OD032207 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SMITH, PETER G · 2022 to 2022
$600k
Circadian Clock Disruption in the Pathogenesis and Therapy of Polycystic Kidney DiseaseR56DK128962 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI RAO, REENA · 2021 to 2021
$100k
NIDDK NIH HHS R01 DK135308NIDDK NIH HHS R56 DK128962NIDDK NIH HHS R56DK128962-01NIDDK NIH HHS RO1DK135308-01NIDDK NIH HHS U54 DK126126NIH HHS S10 OD032207U.S. Department of Defense W81XWH2310011US Department of Defense W81XWH2310011
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39401086
PMCPMC11888963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.