Cerebral Hypoxia During Intermittent Hypoxic-Hyperoxic Training (IHHT): A Case Study Using Cerebral Oximetry Based on Time-Domain Near-Infrared Spectroscopy.

Felix Scholkmann, Daniel Denzler

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In one paragraph

Article in Advances in experimental medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

2 authors.

Felix ScholkmannNeurophotonics and Biosignal Processing Research Group, Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland. Felix.Scholkmann@usz.ch.

Daniel DenzlerMarexum AG, Baar, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn intermittent hypoxia-hyperoxia training (IHHT), air is inhaled through a mask, with the O

aimWe aimed to evaluate the ability of a novel time-domain near-infrared spectroscopy (TD-NIRS) device to measure the effects of IHHT on cerebrovascular oxygenation and haemodynamics. SUBJECT AND

methodsOne subject (41 years old, male, athlete, colleague of the authors) performed an IHHT session as part of his regular training. In parallel, systemic physiological activity (arterial oxygenation (SpO

resultsThe IHHT session caused significant changes in SpO

conclusionsThe case study presented here demonstrates the feasibility of the novel TD-NIRS device to measure changes in cerebrovascular haemodynamics and oxygenation during an IHHT session. It was observed that an intense IHHT session causes significant cerebral hypoxia (decrease of StO

Indexed as

Hypoxia, BrainOximetrySpectroscopy, Near-InfraredAdultCerebrovascular CirculationHumansHyperoxiaHypoxiaMaleOxygenOxygenCerebrovascular oxygenationHaemodynamicsIntermittent hypoxia conditioning (IHC)Oxygen supplyTotal cerebrovascular haemoglobin concentration ([tHb])

Identifiers

PMID39400813

DOI10.1007/978-3-030-34461-0_1

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.