Trial reportAdvances in experimental medicine and biology2024
Dependence of Cerebral Oxygenation and Task Performance on Coloured Light Exposure and Chronotype: Blue and Red Do Not Have the Same Effects on the Prefrontal Cortex.
Trial report in Advances in experimental medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
4 authors.
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Abstract
backgroundIn our previous studies, we investigated the right-left asymmetry (RLA) of cerebral tissue oxygenation (StO
methods36 healthy subjects (22 female, 14 male, age 26.3 ± 5.7 years) were studied twice on two different days. They were exposed to a sequence of blue followed by red light or vice versa in a randomised crossover study design. During CLE, subjects were asked to perform a 2-back task. We measured StO
results(i) We found that the blue and red light caused a RLA in the PFC. For red light exposure, the 2-back performance was negatively correlated with StO
conclusionsWe found for the first time that blue and red light exposure target different regions of the PFC during performance of a 2-back task, which can be explained by the approach and withdrawal model. These results illustrate that studying the subregions (i.e. right, left, and even centre) of the cortex provides a better understanding of the CLE effects in the human brain. Our study also shows that individual chronotype plays an important role in the individual changes in StO
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