Evidence map›Paper›PMID 39400772›Full record

ReviewAnnals of biomedical engineering2025

Cartilage Tissue Engineering in Multilayer Tissue Regeneration.

Hilal Yilmaz, Israa F Abdulazez, Sevda Gursoy, Yagmur Kazancioglu, Cem Bulent Ustundag

Abstract readReview
PubMed Publisher
In one paragraph

Review in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Three-dimensionally-printed biphasic PCL/Regenerative biomaterials · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hilal YilmazHealth Biotechnology Center for Excellence Joint Practice and Research (SABIOTEK), Yildiz Technical University, Istanbul, Turkey. hilaltoptas44@gmail.com.ORCID http://orcid.org/0000-0003-3326-4873
Israa F AbdulazezDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Sevda GursoyHealth Biotechnology Center for Excellence Joint Practice and Research (SABIOTEK), Yildiz Technical University, Istanbul, Turkey.
Yagmur KazanciogluDepartment of Bioengineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Cem Bulent UstundagHealth Biotechnology Center for Excellence Joint Practice and Research (SABIOTEK), Yildiz Technical University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The functional and structural integrity of the tissue/organ can be compromised in multilayer reconstructive applications involving cartilage tissue. Therefore, multilayer structures are needed for cartilage applications. In this review, we have examined multilayer scaffolds for use in the treatment of damage to organs such as the trachea, joint, nose, and ear, including the multilayer cartilage structure, but we have generally seen that they have potential applications in trachea and joint regeneration. In conclusion, when the existing studies are examined, the results are promising for the trachea and joint connections, but are still limited for the nasal and ear. It may have promising implications in the future in terms of reducing the invasiveness of existing grafting techniques used in the reconstruction of tissues with multilayered layers.

Indexed as

CartilageRegenerationTissue EngineeringTissue ScaffoldsAnimalsHumansTracheaEar cartilage tissue engineeringNasal cartilage tissue engineeringTracheal tissue engineering

Identifiers

PMID39400772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.