Evidence map›Paper›PMID 39400726›Full record

ArticleMikrochimica acta2024

Microfluidic-SERS sensing system based on dual signal amplification and aptamer for gastric cancer detection.

Yong Huang, Miao Chen, Fengjuan Jiang, Chengzhe Lu, Qunshan Zhu, Yan Yang, Lei Fu, Limao Li, Jia Liu, Zhenguang Wang and 2 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yong Huang *Department of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Miao Chen *Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, P. R. China.
Fengjuan JiangDepartment of Gastroenterology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Chengzhe LuKangda College of Nanjing Medical University, Lianyungang, 222000, P. R. China.
Qunshan ZhuDepartment of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Yan YangDepartment of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Lei FuDepartment of Pathology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Limao LiDepartment of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Jia LiuDepartment of Gastroenterology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Zhenguang WangDepartment of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China.
Xiaowei CaoInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, 225001, P. R. China.
Wei WeiDepartment of Gastrointestinal Surgery, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, P. R. China. jd.k.kenny@163.com.

Funding

Key Medical Research Projects of Yangzhou Health Commission 2023-1-04Yangzhou Social Development fund YZ2022089
6 · The paper itself

Abstract

Studies have found that matrix metalloproteinase-9 (MMP-9) and interleukin-6 (IL-6) play an important role in tumorigenesis. In order to detect MMP-9 and IL-6 concentrations with high sensitivity and specificity, an efficient microfluidic-SERS sensing system was prepared based on surface-enhanced Raman scattering (SERS). The aptamer recognition-release mechanism and the dual signal amplification strategy were applied in the sensing system. The sensor system was developed using two kinds of nanomaterials with excellent SERS properties, namely gold-coated iron tetroxide particles (Fe

Indexed as

Aptamers, NucleotideGoldLimit of DetectionMatrix Metalloproteinase 9Spectrum Analysis, RamanStomach NeoplasmsBiosensing TechniquesDNA, Single-StrandedHumansInterleukin-6Metal NanoparticlesMicrofluidic Analytical TechniquesAptamers, NucleotideDNA, Single-StrandedGoldIL6 protein, humanInterleukin-6Matrix Metalloproteinase 9MMP9 protein, humanAptamerBiomarkerGastric cancerMicrofluidic chipSERS

Identifiers

PMID39400726

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