Evidence map›Paper›PMID 39400359›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2024

Clinical Utility of Neurophysiologic Classification (and Declassification) of Myoclonus.

Marcus N Callister, Molly C Klanderman, Alyssa Stockard, Charles Van Der Walt, Ashley B Pena, John N Caviness

Abstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Recent advances in clinical neurophysiology of myoclonus.Clinical parkinsonism & related disorders · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcus N CallisterDepartment of Neurology, Mayo Clinic, Scottsdale, Arizona, USA.
Molly C KlandermanDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona, USA.
Alyssa StockardAlix School of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Charles Van Der WaltDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona, USA.
Ashley B PenaDepartment of Neurology, Mayo Clinic, Scottsdale, Arizona, USA.
John N CavinessDepartment of Neurology, Mayo Clinic, Scottsdale, Arizona, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMovement clinical neurophysiology studies can distinguish myoclonus, tremor, and other jerky movements; however, there has been limited demonstration of their real-world clinical impact.

objectiveThe aim was to investigate movement study utility in clarifying movement classification and guiding patient management.

methodA retrospective study of myoclonus-related movement studies was performed.

resultsOf 262 patients referred for consideration of myoclonus, 105 (40%) had myoclonus, 156 (59%) had no myoclonus (the commonest alternative classifications were functional jerks and tremor), and 1 was uncertain. An additional 29 studies identified myoclonus without prior clinical suspicion. A total of 119 of 134 (89%) myoclonus patients had a specific neurophysiologic subtype identified, most commonly cortical (64, 54%). Diagnostic differential narrowed in 60% of patients, and a new diagnosis was made in 42 (14%) patients. Medication changes were made in 151 patients (52%), with improvement in 35 of 51 (67%) with follow-up.

conclusionsMovement studies effectively determined movement classification and identified unsuspected myoclonus, leading to changes in diagnosis and management. © 2024 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Indexed as

MyoclonusAdolescentAdultAgedAged, 80 and overElectroencephalographyElectromyographyFemaleHumansMaleMiddle AgedRetrospective StudiesTremorYoung Adultclassificationdiagnosismovement disordersmyoclonusneurophysiology

Identifiers

PMID39400359
PMCPMC11657012

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.