Evidence map›Paper›PMID 39400286›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

Impact of D-dimer on the outcomes of endovascular thrombectomy for acute ischemic stroke: A systematic review and meta-analysis.

Abdullah Reda, Sherief Ghozy, Mohamed Elfil, Eris Spirollari, Aryan Gajjar, Fawaz Al-Mufti

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdullah RedaDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0009-0005-1298-2034
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5629-3023
Mohamed ElfilDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Eris SpirollariSchool of Medicine, New York Medical College, Valhalla, NY, USA.
Aryan GajjarDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Fawaz Al-MuftiDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.ORCID 0000-0003-4461-7005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThere has been growing data about the association between D-dimer levels and thrombectomy outcomes in acute ischemic stroke patients (AIS) with no cumulative evidence. This systematic review and meta-analysis aim to discuss and analyze the findings of the current studies to provide more robust evidence in this regard.MethodsA systematic search was conducted through PubMed, Web of Science, Embase, and Scopus to retrieve all relevant investigations. A meta-analysis was conducted, and the results were presented in odds ratio (ORs) for binary variables and ratio of means (ROM) for continuous variables, each accompanied by its respective 95% confidence intervals (CIs).ResultsAfter searching and screening, 14 studies were included. The analysis showed that the low D-dimer group had significantly higher rates of favorable functional outcome (OR: 4.40; 95%CI: 2.65-7.30;

Indexed as

Endovascular ProceduresFibrin Fibrinogen Degradation ProductsIschemic StrokeStrokeThrombectomyBiomarkersHumansTreatment OutcomeBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DD-dimerdeep venous thrombosisfunctional outcomehemorrhagerecanalizationstrokethrombectomy

Identifiers

PMID39400286
PMCPMC11559765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.