Evidence map›Paper›PMID 39400085›Full record

ReviewEpigenomics2024

Psychiatry and sensation: the epigenetic links.

Madia Lozupone, Ivana Leccisotti, Mario Altamura, Maria Claudia Moretti, Antonello Bellomo, Antonio Daniele, Vittorio Dibello, Emanuela Resta, Francesco Panza

Abstract readReview
In one paragraph

Review in Epigenomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madia LozuponeDepartment of Translational Biomedicine & Neuroscience "DiBraiN", University of Bari Aldo Moro, Bari, 70124, Italy.ORCID 0000-0002-1674-9724
Ivana LeccisottiPsychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, 71122, Italy.
Mario AltamuraPsychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, 71122, Italy.
Maria Claudia MorettiPsychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, 71122, Italy.
Antonello BellomoPsychiatric Unit, Department of Clinical & Experimental Medicine, University of Foggia, Foggia, 71122, Italy.
Antonio DanieleDepartment of Neuroscience, Catholic University of Sacred Heart, Rome, 00147, Italy.
Vittorio DibelloDepartment of Orofacial Pain & Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam & Vrije Universiteit Amsterdam, Amsterdam, 1105 1081 HV, the Netherlands.
Emanuela RestaTranslational Medicine & Health System Management, Department of Economy, University of Foggia, Foggia, 71122, Italy.
Francesco PanzaDepartment of Interdisciplinary Medicine, "Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, Bari, 70124, Italy.ORCID 0000-0002-7220-0656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A complex interaction among sensory, social and epigenetic determinants in psychiatric conditions was described across all age strata. The high prevalence of mental disorders in individuals with sensory deficits might be attributed to the interaction among social isolation, cognitive functioning and sensory processing. The epigenetic implications of such interactions were examined: environmental and social factors can affect gene expression and impact the pathogenesis of psychiatric disorders also through sensory processing. This article discussed the role of social determinants, in other words, social isolation, loneliness and chronic stress, in promoting psychiatric disorders and, in a vicious circle, sensory deficits (vision, hearing, olfaction and somatosensation). We emphasized the importance of integrating social, sensory and epigenetic factors to target different treatments for psychiatric conditions.

Indexed as

Epigenesis, GeneticMental DisordersHumansSensationSocial IsolationStress, Psychologicalcognitive impairmentdepressionDNA methylationepigeneticslate-onset depressionpsychiatryschizophreniasensory impairment

Identifiers

PMID39400085
PMCPMC11534141

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.