Evidence map›Paper›PMID 39399828›Full record

ArticleInternational journal of nanomedicine2024

Fe-HCOF-PEG

Hui Peng, Qian Jiang, Wenhao Mao, Zhonglan Hu, Qi Wang, Zhuo Yu, Li Zhang, Xinyan Wang, Chunbo Zhuang, Jia Mai and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hui Peng *Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Qian Jiang *Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Wenhao Mao *Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Zhonglan Hu *Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Qi WangDepartment of Pharmacy, Kaifeng Hospital of Traditional Chinese Medicine, Kaifeng, 475000, People's Republic of China.
Zhuo YuDepartment of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Li ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Xinyan WangDepartment of Obstetrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Chunbo ZhuangDepartment of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Jia MaiDepartment of Laboratory Medicine, West China Second Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Zhiyuan WangHenan Institute of Advanced Technology, Zhengzhou University, Zhengzhou, 450001, People's Republic of China.
Ting SunDepartment of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.ORCID 0000-0002-4200-9551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The hypoxic tumor microenvironment and single mechanisms severely limit the photodynamic therapy (PDT) efficiency of covalent organic framework (COF) nanoparticles in cancer treatment. Purpose: Here, we propose an iron-loaded, hydrophilic 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000)-modified hollow covalent organic framework (HCOF), Fe-HCOF-PEG Results: Fe-HCOF-PEG Conclusion: To our knowledge, Fe-HCOF-PEG

Indexed as

FerroptosisIronPhotochemotherapyPhotosensitizing AgentsPolyethylene GlycolsReactive Oxygen SpeciesAnimalsCell Line, TumorFemaleHumansMetal-Organic FrameworksMiceMice, Inbred BALB CNeoplasmsPhosphatidylethanolaminesTumor Microenvironment1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)IronMetal-Organic FrameworksPhosphatidylethanolaminesPhotosensitizing AgentsPolyethylene GlycolsReactive Oxygen Speciescancer cellsferroptosisHCOFshypoxiaPDTROS

Identifiers

PMID39399828
PMCPMC11468433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.