Evidence map›Paper›PMID 39399821›Full record

ArticleIntegrative medicine research2024

Herbal extract (

SoYoung Ahn, Parivash Jamrasi, Byunggul Lim, Ji-Won Seo, Xinxing Li, Shu Jiang, Yunho Sung, Seo Hyun Ahn, Chaeyoung Shin, Dongjin Noh and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Integrative medicine research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

SoYoung AhnHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Parivash JamrasiHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Byunggul LimHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Ji-Won SeoHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Xinxing LiHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Shu JiangHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Yunho SungHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Seo Hyun AhnHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Chaeyoung ShinHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.
Dongjin NohR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Bora JinR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Seonjoo LeeR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Ki Won LeeR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Jin Soo KimR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Young Tae KooR&D Center, Kwangdong Pharmaceutical Co., Ltd., Seoul, Republic of Korea.
Wook SongHealth and Exercise Science Laboratory, Department of Physical Education, Seoul National University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic fatigue syndrome (CFS) reduces the health-related quality of life in the working-age population; however, studies have rarely investigated this group. A mixture of Cervus elaphus Linnaeus, Angelica gigas Nakai, and Astragalus membranaceus Bunge (CAA) may be an effective anti-fatigue supplement. However, few clinical trials have explored the anti-fatigue effects of herbal medicines in human participants. Therefore, this study aimed to investigate the effects of the CAA herbal complex on muscle fatigue and endurance capacity in a randomized, placebo-controlled, double-blind trial. Methods: In an 8-week trial, 80 patients with chronic fatigue symptoms were randomly assigned to the CAA (43.5 ± 1.2 years) or placebo group (41.8 ± 1.3 years). Fatigue and cardiorespiratory endurance were measured at baseline, interim, and post-intervention. Fatigue-related blood biomarkers were assessed before and at the end of the intervention. Results: A significant improvement in overall fatigue scores was observed on the fatigue severity scale ( Conclusion: CAA positively and significantly affected fatigue and cardiorespiratory endurance in patients with chronic fatigue, suggesting the potential use of herbal supplements for treating chronic fatigue. Trial registration: Clinical Research Information Service (CRIS, https://cris.nih.go.kr/): KCT0005613.

Indexed as

Angelica gigas nakaiAnti-fatigueAstragalus membranaceus bungeCervus elaphus LinnaeusExercise performance

Identifiers

PMID39399821
PMCPMC11465177

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.