Evidence map›Paper›PMID 39399709›Full record

ArticleTranslational pediatrics2024

Association of serum interleukin-17 level and

Nontaphat Leerach, Sutthirat Sitthisak, Thawatchai Kitti, Nattawat Teerawattanapong, Wiriya Mahikul, Supaporn Lamlertthon, Nathorn Chaiyakunapruk, Kannipa Tasanapak

Abstract read
In one paragraph

Article in Translational pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Association betweenTranslational pediatrics · 2025
    Article
  7. Article
  8. Article
  9. Biomarkers associated with the diagnosis and prognosis ofFrontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Nontaphat LeerachPrincess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-1927-0855
Sutthirat SitthisakDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.
Thawatchai KittiDepartment of Oriental Medicine, Chiang Rai College, Chiangrai, Thailand.
Nattawat TeerawattanapongDepartment of Clinical Pharmacy, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand.
Wiriya MahikulPrincess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Supaporn LamlertthonDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.
Nathorn ChaiyakunaprukDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.
Kannipa TasanapakDepartment of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand.ORCID https://orcid.org/0009-0000-5910-3483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The protocol has been registered in PROSPERO (CRD42023489451). A literature search was conducted in PubMed, EMBASE, Scopus, and Web of Science from inception to October 2023. A meta-analysis was performed to pool the mean difference (MD) with 95% confidence intervals (CIs) of IL-17 levels between patients and controls. Publication bias was assessed, and the risk of bias was evaluated using the Newcastle-Ottawa Scale (NOS). Results: Out of 207 records, 10 studies were included in the review and 9 studies were included in the meta-analysis. Of these, 7 studies compared IL-17 in general MPP patients with controls, 6 studies compared severe MPP patients with mild MPP patients. Serum IL-17 levels were significantly elevated in general MPP patients compared with control (MD =33.94 pg/mL, 95% CI: 24.66, 43.22 pg/mL, P=0.01, I Conclusions: Our meta-analysis revealed that serum IL-17 levels are significantly elevated in pediatric with general and severe MPP. IL-17 might be a potential biomarker or therapeutic target for pneumonia caused by

Indexed as

Interleukin-17 (IL-17)Mycoplasma pneumoniae (M. pneumoniae)Mycoplasma pneumoniae pneumonia (MPP)pediatric

Identifiers

PMID39399709
PMCPMC11467231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.