Evidence map›Paper›PMID 39399651›Full record

ArticleCurrent research in parasitology & vector-borne diseases2024

Evaluation of bio-efficacy of field-aged novel long-lasting insecticidal nets (PBO, chlorfenapyr or pyriproxyfen combined with pyrethroid) against

Jackline L Martin, Louisa A Messenger, Edmund Bernard, Monica Kisamo, Patric Hape, Osca Sizya, Emmanuel Festo, Wambura Matiku, Victoria Marcel, Elizabeth Malya and 7 more

Abstract read
In one paragraph

Article in Current research in parasitology & vector-borne diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Impact of Insecticide-Treated Nets onTropical medicine and infectious disease · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jackline L MartinDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Louisa A MessengerDepartment of Disease Control, Faculty of Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Edmund BernardDepartment of Parasitology, National Institute for Medical Research, BOX 1462, Mwanza, Tanzania.
Monica KisamoDepartment of Parasitology, National Institute for Medical Research, BOX 1462, Mwanza, Tanzania.
Patric HapeDepartment of Parasitology, National Institute for Medical Research, BOX 1462, Mwanza, Tanzania.
Osca SizyaDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Emmanuel FestoDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Wambura MatikuDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Victoria MarcelDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Elizabeth MalyaDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Tatu AzizDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Nancy S MatowoDepartment of Disease Control, Faculty of Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Jacklin F MoshaDepartment of Parasitology, National Institute for Medical Research, BOX 1462, Mwanza, Tanzania.
Franklin W MoshaDepartment of Parasitology, Pan-African Malaria Vector Research Consortium, Kilimanjaro Christian Medical University College, BOX 2240, Moshi, Tanzania.
Mark RowlandDepartment of Disease Control, Faculty of Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
Alphaxard ManjuranoDepartment of Parasitology, National Institute for Medical Research, BOX 1462, Mwanza, Tanzania.
Natacha ProtopopoffDepartment of Disease Control, Faculty of Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation insecticide-treated bed nets (ITNs) combining two insecticides or an insecticide with a synergist are vital in combating malaria, especially in areas with pyrethroid-resistant mosquitoes where standard pyrethroid long-lasting insecticidal net (LLIN) may be less effective. A community durability study was conducted in Misungwi, Tanzania, during a cluster randomised controlled trial. This study assessed the bio-efficacy of three net brands combining a pyrethroid insecticide and either a synergist PBO for Olyset Plus, or a second insecticide pyriproxyfen for Royal Guard, and chlorfenapyr for Interceptor G2 over three years. These nets were compared to Interceptor, a standard pyrethroid-only net. A total of 1950 nets were enrolled across 10 clusters in each treatment arm. Thirty nets per type were collected every 6 months up to 30 months, with 50 nets sampled at 36 months. WHO cone bioassays and tunnel tests were performed at 0, 12, 24, 30 and 36 months. Both susceptible

Indexed as

Bio-efficacyCone assaysDual-active ingredient insecticide-treated netsInsecticide resistanceLong-lasting insecticidal netsMalaria vectorsTanzaniaTunnel test

Identifiers

PMID39399651
PMCPMC11470491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.