Evidence map›Paper›PMID 39398783›Full record

ArticleCureus2024

Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Functional Outcome in Patients With Intracerebral Hemorrhage (ICH) and Its Comparison With ICH Score: A Hospital-Based Study.

Suvarthi Ray, Vijay Kumar, Ratnadeep Biswas, Vishnu S Ojha, Divendu Bhushan, Ravi Kirti, Sanjeev Kumar

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In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Suvarthi RayDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Vijay KumarDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Ratnadeep BiswasDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Vishnu S OjhaDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Divendu BhushanDepartment of Emergency Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Ravi KirtiDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.
Sanjeev KumarDepartment of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe neutrophil-to-lymphocyte ratio (NLR) signifies systemic inflammation, which may correlate with worse outcomes in intracerebral hemorrhage (ICH) patients. This study explored NLR as a prognostic marker of functional outcomes in ICH and compared it with the ICH score.

methodsThis cross-sectional study was conducted at a tertiary-care hospital in India. Blood was collected from patients with ICH to calculate NLR. Functional outcomes were evaluated using the modified Rankin Scale (mRS) at discharge and 90 days follow-up.

resultsThe area under receiver operating characteristic curve (AUROC) for NLR predicting poor mRS scores (3-6) at discharge was 0.695 (p = 0.109), and at follow-up, it was 0.729 (p < 0.001) with a cut-off of ≥7.2, sensitivity 68%, and specificity 72%. The AUROC for ICH score was 0.846 (p = 0.003) at discharge and 0.845 (p < 0.001) at follow-up. DeLong's test indicated the ICH score had significantly better predictive performance than NLR at follow-up (p = 0.018).

conclusionsNLR is a potential prognostic marker for ICH outcomes, showing significant predictive value at 90 days follow-up. However, the ICH score remains a more reliable predictor. Integrating NLR into the ICH score may enhance its prognostic accuracy, but further validation in multicentric studies is needed.

Indexed as

functional outcomeintracerebral hemorrhageintracerebral hemorrhage scoremodified rankin scaleneutrophil-to-lymphocyte ratioprognosisstroke

Identifiers

PMID39398783
PMCPMC11471280

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