ArticleCureus2024
Mechanism of Action of Green-Synthesized Silver Nanoparticle-Incorporated Dental Varnish Against Candida albicans.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of silver and vanadium-based antibiofilm agents: mechanisms and efficacy in oral biofilms.Future microbiology · 2025Pooled it
- Silver nanoparticles in biomedicine: green synthesis, precision theranostics, and future clinical translation.Folia microbiologica · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMATERIALS AND
methodsAgNPs were synthesized via a green synthesis method using
resultsThe AgNP-incorporated dental varnish demonstrated significant antifungal activity against DISCUSSION: The results suggest that the antifungal activity of the AgNP-incorporated dental varnish is mediated through multiple mechanisms, including membrane disruption, increased permeability leading to protein and cytoplasmic leakage, and possibly the generation of reactive oxygen species (ROS). The varnish's efficacy was comparable to that of commercial antifungal dental varnishes, highlighting its potential as a viable alternative in dental applications.
conclusionGreen-synthesized AgNPs, when incorporated into dental varnish, exhibit potent antifungal activity against
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.