Evidence map›Paper›PMID 39398732›Full record

ArticleCureus2024

Diagnosis and Prognostic Implications of Primary Intraosseous Carcinoma: A Case Report and Literature Review.

Nicholas A McDonald, William Montagne, Sonal Shah, Joshua J Goldman, Jo-Lawrence Bigcas

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas A McDonaldOtolaryngology, Washington State University, Spokane, USA.
William MontagneOtolaryngology-Head and Neck Surgery, University of Nevada Las Vegas School of Medicine, Las Vegas, USA.
Sonal ShahOral and Maxillofacial Surgery, University of Nevada Las Vegas School of Medicine, Las Vegas, USA.
Joshua J GoldmanPlastic Surgery, Vegas Plastic Surgery Institute, Las Vegas, USA.
Jo-Lawrence BigcasOtolaryngology-Head and Neck Surgery, University of Nevada Las Vegas School of Medicine, Las Vegas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary Intraosseous Carcinoma (PIOC) is a rare and aggressive squamous cell carcinoma (SCC) derived from remnants of odontogenic epithelium with no initial connection to oral mucosa. Due to the rarity of the disease, etiology and epidemiology are not clearly defined. The most affected site is the posterior mandible, and clinical features include swelling of the jaw, jaw pain, and sensory disturbances. Given the similarities of PIOC to other odontogenic carcinomas, diagnosis is often difficult, resulting in delays in intervention. Treatment of PIOC of the mandible includes surgery alone, surgery with adjuvant radiotherapy or chemotherapy, and free flap reconstruction. PIOC prognosis is poor, with the lymph nodal status acting as an important indicator. We present a case of a 60-year-old female who presented with a left submandibular mass initially thought to be SCC of unknown primary origin. Further investigation led to a final diagnosis of PIOC of the mandible. Clinical, radiological, and histological features of PIOC will be discussed.

Indexed as

carcinoma of unknown primary (cup)mandibular carcinomaprimary intraosseous carcinomasquamous cell carcinoma of unknown primarysquamous cell carcinoma (scc)

Identifiers

PMID39398732
PMCPMC11467765

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.