Evidence map›Paper›PMID 39398715›Full record

ArticleCureus2024

CT-Based Adaptive Short Course Radiotherapy for Rectal Cancer: A Case Report.

Jonathan Henning, Sylvia Choo, Pranit Singh, Gage Redler, Russell F Palm

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adaptive radiotherapy for gastrointestinal malignancies.Radiation oncology (London, England) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan HenningRadiation Oncology, University of South Florida Morsani College of Medicine, Tampa, USA.
Sylvia ChooRadiation Oncology, University of South Florida Morsani College of Medicine, Tampa, USA.
Pranit SinghRadiation Oncology, University of South Florida Morsani College of Medicine, Tampa, USA.
Gage RedlerRadiation Oncology, Moffitt Cancer Center, Tampa, USA.
Russell F PalmRadiation Oncology, The Ohio State University Wexner Medical Center, Columbus, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rectal cancer is a highly prevalent malignancy with an increasing number of treatment strategies and sequencing. Short-course radiotherapy (SCRT) combined with chemotherapy has shown to be a feasible treatment option for non-metastatic disease within the total neoadjuvant therapy paradigm. In contrast to conventionally fractionated chemoradiation, SCRT carries less logistical burden and reduces time off systemic therapy, which is particularly beneficial for patients with metastatic disease. We present a case of a 42-year-old male with metastatic rectal cancer who received SCRT using CT-based adaptive radiation, delivering 25 Gy to the pelvis with a simultaneous integrated boost of 30 Gy to the rectal tumor over five treatments. CT-based adaptive radiation was effective and well-tolerated and offers a pathway towards isotoxic radiotherapy dose escalation for patients considered to be inoperable. This case demonstrates the integration of adaptive SCRT as a promising strategy for rectal cancer.

Indexed as

adaptive radiationmedical physicsmetastatic rectal cancerradiation therapy technologyrectal cancershort course radiation

Identifiers

PMID39398715
PMCPMC11470755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.