Evidence map›Paper›PMID 39398713›Full record

ArticleCureus2024

The Vital Role of Immunohematology in Diagnosing Paroxysmal Cold Hemoglobinuria: A Clinical Case Report.

Willy Nava Gutiérrez, Paola Villa Cortés, Ricardo Ramírez Morales, Juan P Espinoza Garza, Jaime E Espinosa Mora

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Willy Nava GutiérrezHematology and Oncology, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Nuevo León (ISSSTELEON), Monterrey, MEX.
Paola Villa CortésCritical Care Medicine, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Nuevo León (ISSSTELEON), Monterrey, MEX.
Ricardo Ramírez MoralesRheumatology, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Nuevo León (ISSSTELEON), Monterrey, MEX.
Juan P Espinoza GarzaPulmonology, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Nuevo León (ISSSTELEON), Monterrey, MEX.
Jaime E Espinosa MoraInfectious Disease, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado de Nuevo León (ISSSTELEON), Monterrey, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune hemolytic anemia caused by the binding of IgG immunoglobulins to red blood cells at cold temperatures, leading to hemolysis upon rewarming. The Donath-Landsteiner test can show biphasic hemolysis, leading to diagnosis. There is no consensus, but chemoimmunotherapy with or without plasma exchange is commonly employed. We present the case of a 42-year-old male who experienced symptoms of hemolysis after cold exposure in a semi-arid, warm-climate city.

Indexed as

anca-negativeautoimmune hemolytic anemia (aiha)autoimmune vasculitiscold agglutinin diseasecomplement-mediated hemolysiseculizumabmexicoparoxysmal cold hemoglobinuria (pch)rituximabtherapeutic plasma exchange (tpe)

Identifiers

PMID39398713
PMCPMC11471295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.