ArticleCureus2024
Effectiveness of Papain-Based Organic Dentifrices Versus Commercial Whitening Dentifrice on Tea-Induced Tooth Stains: An In Vitro Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Effects of Bromelain and Papain in Tooth Whitening and Caries Removal: A Literature Review.Dentistry journal · 2025Review
- Whitening Efficiency of Papain and Bromelain Gels in Removing Dental Stains.Gels (Basel, Switzerland) · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTooth discoloration is a common issue for oral health practitioners. Whitening treatments remove surface and deep stains using either chemicals or over-the-counter products. Due to harmful chemical effects, organic whitening products are increasingly preferred. This study compared the effectiveness of organic papain-based dentifrices (Perfora Magic Teeth Whitening Serum, Gurugram, India) on tea stains to commercially available Colgate whitening dentifrices (Colgate-Palmolive, New York, NY).
methodsSixty maxillary central incisors for periodontal reasons were used and divided into two groups. Each sample was soaked in freshly brewed tea for 10 minutes daily and stored in artificial saliva (Nanochemazone, Kurukshetra, India) for 24 hours. After four weeks, group 1 was treated with papain-based dentifrices, and group 2 with Colgate Visible White teeth whitening paste (CVWP) daily for four weeks. Spectrophotometric analysis (VITA Easyshade V, VITA Zahnfabrik, Bad Säckingen, Germany) was performed pre-treatment and at four weeks post-treatment. Data were compiled and statistically analyzed.
resultsCompared with group 1, group 2 exhibited an optimal color change (ΔE). Statistically significant differences were observed between the mean ΔL (lightness) and Δb (blueness -b or yellowness +b) values.
conclusionCVWP showed better color achievement and stain reduction due to abrasive and peroxide components. Although Perfora Teeth Whitening Serum has low efficacy in upgrading the color of the enamel surface, it is safe for long-term use.
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Registered trials
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