Evidence map›Paper›PMID 39398615›Full record

ArticleAmerican journal of translational research2024

Prognostic value of the Controlling Nutritional Status score in patients with newly diagnosed multiple myeloma.

Yan Li, Ling-Zhijie Kong

Abstract read
In one paragraph

Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yan LiDepartment of Hematology, Hebei General Hospital Shijiazhuang 050051, Hebei, The People's Republic of China.
Ling-Zhijie KongDepartment of Hematology, Hebei General Hospital Shijiazhuang 050051, Hebei, The People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is some evidence indicating that the Controlling Nutritional Status (CONUT) score is a prognostic factor in patients with hematological malignancies, including multiple myeloma (MM). The aim of this study was to assess the prognostic value of the CONUT score in newly diagnosed MM.

methodWe retrospectively investigated multiple clinical variables, including the CONUT score, age, sex, body mass index, M protein type, International Staging System (ISS) stage, Durie-Salmon (DS) stage, and blood cell count, in 58 patients with newly diagnosed MM.

resultThere was a significant correlation between a high CONUT score (>5.5) and poor OS. The prognostic impact of this score was more significant in patients with a low ISS or DS stage. In univariate analysis, the white blood cell count (P=0.021), monocyte count (P=0.022), eosinophil count (P=0.004), and lactic dehydrogenase (LDH) (P=0.042) predicted OS. Multivariate analysis identified the CONUT score (P=0.012), monocyte count (P=0.008), eosinophil count (P=0.031), and LDH (P=0.001) to be independent prognostic factors for overall survival (OS).

conclusionThe CONUT score is a useful prognostic indicator in patients with MM, especially those with a low ISS or DS stage. The monocyte count, eosinophil count, and LDH are independent prognostic factors in these patients.

Indexed as

CONUT scoreMultiple myelomaoverall survivalprognosis

Identifiers

PMID39398615
PMCPMC11470358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.