ArticleAmerican journal of translational research2024
Baseline absolute lymphocyte count as a prognostic indicator in advanced or metastatic breast cancer: a systematic review and meta-analysis.
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
This study used meta-analysis to examine the role of baseline absolute lymphocyte count (ALC) in the prognosis of advanced breast cancer (ABC) or metastatic breast cancer (MBC). A comprehensive search encompassing PubMed, The Cochrane Library, Embase, and Web of Science databases was undertaken to identify and screen literature based on predefined inclusion and exclusion criteria. Progression-free survival (PFS), time to treatment failure (TTF), post-progression survival (PPS), and overall survival (OS) were selected as outcome measures. A meta-analysis of 14 studies, involving 2,540 patients and employing Review Manager 5.3 and Stata 14.0, was conducted. Notably, 12 of these studies originated from Japan. The findings indicated that patients with ABC or MBC exhibiting high ALC had significantly improved PFS, TTF, PPS (hazard ratio [HR] = 0.53, 95% confidence interval [CI]: 0.45-0.62,
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