ArticleAmerican journal of translational research2024
The relationship between vitamin A and E levels and the severity of disease and oxidative stress injury in patients with preeclampsia.
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Efficacy of Vitamin E Supplementation During Pregnancy on the Vitamin E Nutritional Status of the Mother-Child Dyad: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.Food science & nutrition · 2026Review
- Oxidative Stress and Antioxidant Status in Pregnant Women with Gestational Diabetes Mellitus and Late-Onset Complication of Pre-Eclampsia.International journal of molecular sciences · 2025Article
- Serum creatinine, uric acid, and D-dimer levels as predictors of disease severity in hypertensive disorders of pregnancy.American journal of translational research · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the correlation of vitamin A (VA) and vitamin E (VE) levels with preeclampsia (PE) severity and oxidative stress injury in patients.
methodsClinical data from 93 PE patients who established health records and delivered newborns at Xingtai People's Hospital between January 2017 and September 2019 were retrospectively analyzed. The patients were categorized into mild a PE group (n = 51) and severe a PE group (n = 42) based on the severity of their condition, and also into an early-onset PE group (n = 38, gestational weeks < 34) and a late-onset PE group (n = 55, gestational weeks ≥ 34) by the timing of onset. Additionally, 50 healthy pregnant women undergoing routine prenatal check-ups during the same period were selected as the control group. Pearson's correlation was used to analyze the correlation of VA and VE levels with blood lipids, liver and kidney functions, and oxidative stress injury indices in PE patients. Receiver operator characteristic (ROC) curves were plotted to assess the value of serum VA and VE levels in evaluating early-onset PE and adverse pregnancy outcomes in PE patients.
resultsPearson correlation analysis revealed that VA and VE levels in PE patients had negative correlation with total cholesterol (
conclusionsSerum VA and VE levels are closely related to PE severity, lipid levels, renal function, AOPP, and other oxidative stress injury markers in PE patients. Combined detection of VA and VE levels can help assess early-onset PE and adverse pregnancy outcomes.
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