Evidence map›Paper›PMID 39398425›Full record

ArticlePhenomics (Cham, Switzerland)2024

Identification of Key Factors in Cartilage Tissue During the Progression of Osteoarthritis Using a Non-targeted Metabolomics Strategy.

Shiyu Sun, Minghui Chen, Tingting Zhang, Yanyan Wang, Weijun Shen, Tao Zhang, Jian Liu, Haidan Lan, Jianyuan Zhao, Fuqing Lin and 1 more

Abstract read
In one paragraph

Article in Phenomics (Cham, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Eosinophils in Rheumatoid Arthritis: A Multifaceted Role in the Pathogenesis of the Disease.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2025
    Article
  5. Review
  6. Article
  7. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shiyu Sun *Department of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0009-0005-3955-4021
Minghui Chen *Department of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0003-2014-3204
Tingting Zhang *Department of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0009-0001-9980-6340
Yanyan WangDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0009-0009-7394-2270
Weijun ShenDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0003-2676-2305
Tao ZhangDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0001-9628-683X
Jian LiuDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0001-6858-8793
Haidan LanDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0009-0002-4218-3565
Jianyuan ZhaoInstitute for Developmental and Regenerative Cardiovascular Medicine, MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092 China.ORCID 0000-0001-9861-0330
Fuqing LinDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0002-6478-0013
Xuan ZhaoDepartment of Anesthesia, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072 China.ORCID 0000-0002-2670-1660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research was to reveal the key factors in the progression of osteoarthritis (OA) using non-targeted metabolomics and to find targeted therapies for patients with OA. Twenty-two patients with knee OA scheduled for total knee arthroplasty were divided into two groups: Kellgren-Lawrence (KL) grade 3 ( Supplementary Information: The online version contains supplementary material available at 10.1007/s43657-023-00123-z.

Indexed as

Kellgren–Lawrence gradeNon-targeted metabolomicsOsteoarthritisProgression

Identifiers

PMID39398425
PMCPMC11466919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.