Evidence map›Paper›PMID 39398240›Full record

ArticleiScience2024

Expression quantitative trait locus mapping of extracellular microRNAs in human plasma.

Tianxiao Huan, Roby Joehanes, Jian Rong, Ming-Huei Chen, Rima Mustafa, Abbas Dehghan, Mohsen Ghanbari, Hannah Karlin, Shih-Jen Hwang, Paul Courchesne and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tianxiao HuanThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Roby JoehanesThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Jian RongDepartment of Mathematics and Statistics, Boston University, Boston, MA 02118, USA.
Ming-Huei ChenThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Rima MustafaDepartment of Epidemiology and Biostatistics, Imperial College London, London SW7 2AZ, UK.
Abbas DehghanDepartment of Epidemiology and Biostatistics, Imperial College London, London SW7 2AZ, UK.
Mohsen GhanbariDepartment of Epidemiology, Erasmus MC University Medical Center, 3000 CA Rotterdam, the Netherlands.
Hannah KarlinThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Shih-Jen HwangThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Paul CourchesneThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Martin G LarsonDepartment of Mathematics and Statistics, Boston University, Boston, MA 02118, USA.
Andrew D JohnsonThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.
Jane E FreedmanSchool of Medicine, Vanderbilt University, 1161 21st Avenue S, Nashville, TN 37232, USA.
Daniel LevyThe National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt. Wayte Avenue, Framingham, MA 01702, USA.

Funding

THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195
6 · The paper itself

Abstract

MicroRNAs, crucial in regulating protein-coding gene expression, are implicated in various diseases. We performed a genome-wide association study of plasma miRNAs (ex-miRNAs) in 3,743 Framingham Heart Study (FHS) participants and identified 1,027

Indexed as

Association analysisBody substance sampleGenomicsQuantitative geneticsTranscriptomics

Identifiers

PMID39398240
PMCPMC11471191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.