Evidence map›Paper›PMID 39397991›Full record

ArticleHeliyon2024

Glycyrrhetinic acid reduces lung inflammation caused by pneumococcal infection by reducing the toxicity of pneumolysin.

Yan Xu, Ying Ding, Hongji Wu, Donglin Li, Yudi Li, Yibo Hu, Haoji Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan XuDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Ying DingDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Hongji WuDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Donglin LiDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Yudi LiDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Yibo HuDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.
Haoji MengDepartment of Pediatrics, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In this study, to provide new methods for the treatment of Methods: A mouse model was established via intranasal administration of Results: Glycyrrhetinic acid reduced the levels of inflammatory factors, the dry‒wet ratio, the abundance of Conclusion: Glycyrrhetinic acid can reduce the virulence of

Indexed as

Glycyrrhetinic acidLung inflammationPLYPneumolysin

Identifiers

PMID39397991
PMCPMC11471213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.