Evidence map›Paper›PMID 39397970›Full record

ArticleHeliyon2024

N-alkylation of amines for the synthesis of potential antiviral agents: A structural modification approach.

Nadia Arrousse, Elyor Berdimurodov, Mariia Bogacheva, Fathiah Zakham, Soukaina Esslali, Sghir El Kadiri, Mustapha Taleb, Olli Vapalahti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadia ArrousseSchool of Science and Engineering, Al Akhawayn University in Ifrane, Hassan II avenue, 53000 Ifrane, Morocco.
Elyor BerdimurodovFaculty of Chemistry, National University of Uzbekistan, Tashkent, 100034, Uzbekistan.
Mariia BogachevaViral Zone Research Unit, Faculty of Medicine, University of Helsinki, Finland.
Fathiah ZakhamDepartment of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Soukaina EsslaliLaboratory of Chemistry-Biology Applied to the Environment, Chemistry Department, Faculty of Sciences, Moulay-Ismail University, B.P. 11201, Zitoune, Meknes, Morocco.
Sghir El KadiriLaboratory of Applied Chemistry & Environment (LCAE), Faculty of Science, Mohammed First University, Oujda, Morocco.
Mustapha TalebLaboratory of Engineering, Electrochemistry, Modelling and Environment (LIEME), Faculty of Sciences, University Sidi Mohamed Ben Abdellah, Fez, Morocco.
Olli VapalahtiDepartment of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The threat of emerging viral outbreaks has increased the need for fast and effective development of therapeutics against emerging pathogens. One approach is to modify the structure of existing therapeutic agents to achieve the desired antiviral properties. Here, we attempted to synthesize a new antiviral compound by modifying the structure of chloroquine using the

Indexed as

ChloroquineDrug synthesisMolecular dockingPharmacokinetic properties

Identifiers

PMID39397970
PMCPMC11470537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.