Evidence map›Paper›PMID 39397929›Full record

ArticleHeliyon2024

Effects of natural reduced water on cognitive functions in older adults: A RCT study.

Takamitsu Shinada, Keisuke Kokubun, Yuji Takano, Hikari Iki, Koki Kobayashi, Takeki Hamasaki, Yasuyuki Taki

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takamitsu ShinadaSmart-Aging Research Center, Tohoku University, Sendai, 980-8575, Japan.
Keisuke KokubunSmart-Aging Research Center, Tohoku University, Sendai, 980-8575, Japan.
Yuji TakanoSmart-Aging Research Center, Tohoku University, Sendai, 980-8575, Japan.
Hikari IkiDepartment of Aging Research and Geriatric Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, 980-8575, Japan.
Koki KobayashiDepartment of Aging Research and Geriatric Medicine, Institute of Development, Aging and Cancer, Tohoku University, Sendai, 980-8575, Japan.
Takeki HamasakiLaboratory of Functional Water, Food and Energy, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, 812-8581, Japan.
Yasuyuki TakiSmart-Aging Research Center, Tohoku University, Sendai, 980-8575, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and diabetes increase the risk of cognitive decline and dementia. Natural reduced water contains active hydrogen (hydrogen radicals), eliminates reactive oxygen species, and has antidiabetic effects. However, whether natural reduced water affects human cognitive function is unknown. Therefore, we implemented a double-blind intervention experiment in which participants consumed 1 L of natural reduced water or tap water daily for 6 months. The participants were healthy older adults living in Japan. The intervention group showed significant improvements in cognitive functions of attention function (p < 0.01) and short-term memory (p < 0.05). These results indicate that the continuous intake of natural reduced water improves several cognitive functions.

Identifiers

PMID39397929
PMCPMC11471180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.