Evidence map›Paper›PMID 39397801›Full record

ArticleOncology letters2024

Pre‑operative mean platelet volume is associated with overall survival in patients with IDH‑wildtype glioblastoma undergoing maximal safe resection.

Silvia Snider, Pierfrancesco De Domenico, Francesca Roncelli, Andrea Bisoglio, Matteo Braga, Anna Ghelfi, Lina Raffaella Barzaghi, Cinzia Mura, Pietro Mortini, Filippo Gagliardi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silvia SniderDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Pierfrancesco De DomenicoDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Francesca RoncelliDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Andrea BisoglioDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Matteo BragaDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Anna GhelfiDepartment of Neurosurgery, Duke University, Durham, NC 27701, USA.
Lina Raffaella BarzaghiDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Cinzia MuraDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Pietro MortiniDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.
Filippo GagliardiDepartment of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), I-20132 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most common, fast-growing, and aggressive malignant primary CNS tumor, with a survival time of ~15 months despite the use of surgery and adjuvant treatments. In recent years, there has been a growing interest in exploring the potential contribution of hemostasis and platelet activation in GBM biology. The present study assessed the association between the pre-operative coagulation profile [as indicated by prothrombin time (PT) ratio and activated partial thromboplastin time (aPTT) ratio], overall platelets (PLT) count and the mean platelet volume (MPV) with tumoral characteristics and overall survival in patients with isocitrate dehydrogenase-wildtype (IDH-wt) GBM.

Indexed as

activated plateletsglioblastomahigh-grade gliomamean platelet volumeplatelets

Identifiers

PMID39397801
PMCPMC11467840

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.