Evidence map›Paper›PMID 39397463›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2024

[Flow cytometry analysis of normal range of natural killer cells and their subsets in peripheral blood of healthy Chinese adults].

Jiayi Tian, Yixue Guo, Xia Zhang, Xiaolin Sun, Jing He

Abstract readEnglish Abstract
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jiayi TianDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Yixue GuoDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Xia ZhangDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Xiaolin SunDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
Jing HeDepartment of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the distribution characteristics of natural killer (NK) cells and their subsets in normal peripheral blood in China, and to explore their normal value and significance.

methodsIn this study, peripheral blood was collected from 200 healthy adults. Their age range was 18-87 years. All the subjects were divided into 6 age groups: 18-30, 31-40, 41-50, 51-60, 61-70, and 71-87 years. With CD16, CD56, CD4, CD19, as surface markers, fluid cytology detection techniques were used to detect NK cells and the relative and absolute counts. SPSS 27.0 was used for systematic analysis of the data, and the measurement data were expressed as mean±standard deviations. A

resultsThe range of NK B cells in the 200 healthy adult subjects was (0.46±0.24)×10

conclusionThe detection of NK cells and their subsets has significant reference value for the diagnosis, treatment, and prognosis of autoimmune diseases, infectious diseases, and tumors. This study provides a preliminary reference range for clinical detection of NK cell subsets, but further research with a larger sample size and multi-center trials are needed to confirm these findings.

Indexed as

CD56 AntigenFlow CytometryKiller Cells, NaturalAdolescentAdultAgedAged, 80 and overChinaEast Asian PeopleFemaleHumansLymphocyte CountMaleMiddle AgedReceptors, IgGReference ValuesCD56 AntigenReceptors, IgGNatural killer cellsNatural killer cells and their subsetsNormal value

Identifiers

PMID39397463
PMCPMC11480548

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