ArticleEuropean stroke journal2025
Endovascular treatment versus medical management for basilar artery occlusion with low-to-moderate symptoms (National Institutes of Health Stroke Scale < 10).
Article in European stroke journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Endovascular thrombectomy versus best medical therapy for acute vertebrobasilar artery occlusion in patients with low NIHSS scores: a meta-analysis.Annals of medicine · 2026Pooled it
- Revascularization treatment for posterior circulation ischemic stroke: a systematic review and network meta-analysis.BMC neurology · 2025Pooled it
- Endovascular therapy versus standard medical treatment for vertebrobasilar artery occlusion: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Predictors of Unfavorable Outcome After Endovascular Thrombectomy for Acute Basilar Artery Occlusion with Mild Symptoms.Clinical neuroradiology · 2026Article
- Clinical and Neuroimaging Predictors of Posterior Circulation Stroke: A Retrospective Analysis of In-Hospital Features.Brain sciences · 2026Article
- Outcomes of Endovascular Treatment for Acute Basilar Artery Occlusion With National Institutes of Health Stroke Scale Score ≤10.Journal of the American Heart Association · 2026Article
- Revascularization Treatment of Basilar Artery Occlusion in Patients with Mild-to-Moderate Severe Stroke.Stroke (Hoboken, N.J.) · 2025Article
- Outcomes of Endovascular Treatment in Patients With Vertebrobasilar Artery Occlusion Beyond 24 Hours.JAMA network open · 2025Article
- Admission hyperglycemia effect on symptomatic intracranial hemorrhage in tenecteplase versus alteplase before large vessel occlusion stroke thrombectomy.Journal of neurology · 2024Article
Corrections and comments
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Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with acute basilar artery occlusion (BAO) and low-to-moderate symptoms (National Institutes of Health Stroke Scale [NIHSS] < 10) are poorly represented in thrombectomy trials. Our objective is to compare thrombectomy and best medical management (BMT) in this population.
methodsWe compared data of all consecutive patients presenting with an initial NIHSS < 10 and acute symptomatic BAO included in two registries. The main outcome was the proportion of patients achieving a 3-months favorable outcome (mRS 0-2 or equal to the pre-stroke value). Secondary outcomes included the proportion of patients with an excellent outcome (mRS 0-1 or equal to pre-stroke value), overall mRs distribution (shift analysis) and mortality. Effect sizes for thrombectomy versus BMT alone were calculated using binary or ordinal logistic regression model before after considering confounders using the inverse probability of treatment weighting (IPTW) propensity score method.
resultsOne hundred twenty-seven patients were included: sixty-four patients treated with thrombectomy (mean ± SD age: 63.4 ± 16.1) and sixty-three with BMT (mean ± SD age: 69.0 ± 14.3). There was no significant difference between groups for the rate of 3 month-favorable outcome or mortality. After propensity-score adjustment, thrombectomy was associated with a significantly higher chance of excellent outcome at 3 months (mRS 0-1 or equal to pre-stroke value; adjusted OR, 2.68; 95%CI, 1.04-6.90;
conclusionOur study suggests that thrombectomy in patients with low-to-moderate symptoms (NIHSS < 10) due to BAO does not improve the rate of favorable outcome but could lead to a higher chance of excellent outcome at 3 months.
trial registrationETIS Registry. http://www. CLINICALTRIALS: govNCT03776877.
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