Evidence map›Paper›PMID 39397329›Full record

ArticleNephrology (Carlton, Vic.)2024

NELL-1 membranous nephropathy due to mercury exposure from fairness cream: Report of two cases.

Pankaj Jawandhiya, Ankur Gupta

Abstract readCase Reports
In one paragraph

Article in Nephrology (Carlton, Vic.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. NELL-1: role and mechanisms in disease pathogenesis and development.Frontiers in cell and developmental biology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pankaj JawandhiyaDepartment of Nephrology, Super specialty Hospital, Nagpur, India.ORCID https://orcid.org/0009-0004-2750-0934
Ankur GuptaDepartment of Nephrology, Palmerston North Hospital, Palmerston North, New Zealand.ORCID https://orcid.org/0000-0003-1390-3914

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mercury contained in beauty-enhancing cosmetics can cause chronic poisoning and membranous nephropathy (MN). We report two cases of nephrotic syndrome caused by MN with evidence of mercury poisoning due to the application of fairness cream in a short duration of a few months. The individuals were positive for neural epidermal growth factor-like 1 [NELL-1]. Discontinuation of the use of cosmetic products and modified Ponticelli regimen improved the nephrotic state in these individuals. We suggest that mercury poisoning should be considered in NELL-1-positive individuals with a history of application of beauty products.

Indexed as

Glomerulonephritis, MembranousCalcium-Binding ProteinsHumansMercury PoisoningNephrotic SyndromeNerve Tissue ProteinsSkin CreamTreatment OutcomeCalcium-Binding ProteinsNELL1 protein, humanNerve Tissue Proteinscosmeticfairness creammembranous nephropathymercurynephrotic syndrome

Identifiers

PMID39397329
PMCPMC13546958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.