Evidence map›Paper›PMID 39397231›Full record

ReviewEndocrine2025

Hypoparathyroidism: an update on new therapeutic approaches.

Marco Pitea, Ruggero Lanzafame, Elisa Sala, Ludovica Crocè, Stefano Mora

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco PiteaDepartment of Pediatrics, IRCCS Ospedale San Raffaele, Milano, Italy.
Ruggero LanzafameDepartment of Pediatrics, IRCCS Ospedale San Raffaele, Milano, Italy.ORCID 0009-0009-5378-1895
Elisa SalaDepartment of Pediatrics, IRCCS Ospedale San Raffaele, Milano, Italy.ORCID 0009-0003-0294-8591
Ludovica CrocèDepartment of Pediatrics, IRCCS Ospedale San Raffaele, Milano, Italy.
Stefano MoraDepartment of Pediatrics, IRCCS Ospedale San Raffaele, Milano, Italy. mora.stefano@hsr.it.ORCID 0000-0002-4781-6715

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypoparathyroidism is a rare endocrine disease characterized by insufficient parathyroid hormone (PTH) secretion by the parathyroid glands, leading to hypocalcemia. In contrast to most hormone deficiencies for which hormone replacement is currently the mainstay of therapy, hypoparathyroidism has conventionally been treated with calcium supplements and active analogs of vitamin D. Although the advent of a replacement therapy with 1-34 and 1-84 PTH represented a major step in the therapeutic history of hypoparathyroidism, several new molecules and different management strategies have recently been developed. PURPOSE: This review investigates the therapeutic approaches currently under investigation for the treatment of hypoparathyroidism. Clinical trials results have been considered and discussed.

Indexed as

HypoparathyroidismCalciumHormone Replacement TherapyHumansParathyroid HormoneVitamin DCalciumParathyroid HormoneVitamin DAutosomal dominant hypocalcemiaHypoparathyroidismParathyroid hormoneTreatment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.