Evidence map›Paper›PMID 39397137›Full record

ArticleAIDS and behavior2025

HIV Stigma is Associated with Two-Year Decline in Cognitive Performance Among People with HIV.

Mark K Britton, Micaela Lembo, Yancheng Li, Eric C Porges, Robert L Cook, Ronald A Cohen, Charurut Somboonwit, Gladys E Ibañez

Abstract read
In one paragraph

Article in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mark K BrittonDepartment of Epidemiology, University of Florida, Gainesville, FL, USA. mark.britton@ufl.edu.ORCID http://orcid.org/0000-0003-4261-1806
Micaela LemboDepartment of Epidemiology, Florida International University, Miami, FL, USA.
Yancheng LiDepartment of Epidemiology, University of Florida, Gainesville, FL, USA.
Eric C PorgesCenter for Cognitive Aging and Memory, University of Florida, Gainesville, FL, USA.
Robert L CookDepartment of Epidemiology, University of Florida, Gainesville, FL, USA.
Ronald A CohenCenter for Cognitive Aging and Memory, University of Florida, Gainesville, FL, USA.
Charurut SomboonwitDepartment of Internal Medicine, University of South Florida, Tampa, FL, USA.
Gladys E IbañezDepartment of Epidemiology, Florida International University, Miami, FL, USA.

Funding

Health outcomes and cognitive effects of marijuana use among persons living with HIV/AIDSR01DA042069 · NIDA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2017 to 2021
$3.9M
Translational Science Training to Reduce the Impact of Alcohol on HIV InfectionT32AA025877 · NIAAA · UNIVERSITY OF FLORIDA · PI Robert L Cook, DEBRA E LYON · 2018 to 2026
$3.3M
Southern HIV and Alcohol Research Consortium Biomedical Data RepositoryU24AA029959 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L, WU, SAMUEL S · 2021 to 2025
$2.5M
A Remotely delivered Tai Chi/Qigong Intervention for older people living with HIV: A Randomized Clinical TrialR01AT012590 · NCCIH · FLORIDA INTERNATIONAL UNIVERSITY · PI GLADYS Eulalia IBANEZ · 2024 to 2026
$1.4M
Longitudinal Modeling of Pro-Inflammatory Cytokines, Hazardous Alcohol Use, and Cerebral Metabolites as Predictors of Neurocognitive Change in People with HIVF31AA031440 · NIAAA · UNIVERSITY OF FLORIDA · PI BRITTON, MARK K · 2023 to 2025
$75k
NCCIH NIH HHS R01 AT012590NCCIH NIH HHS R01AT012590NIAAA NIH HHS F31 AA031440NIAAA NIH HHS F31AA031440NIAAA NIH HHS T32 AA025877NIAAA NIH HHS T32AA025877NIAAA NIH HHS U24 AA029959NIDA NIH HHS R01 DA042069NIDA NIH HHS R01DA042069
6 · The paper itself

Abstract

HIV stigma is associated with suboptimal clinical outcomes and has been cross-sectionally linked to cognitive deficits in people with HIV (PWH). However, it is unclear whether HIV stigma precedes cognitive decline or vice versa. We examined associations in 303 adult PWH (mean age 50.01 (11.91) years; 46% female; 67% non-Hispanic Black) between the abbreviated Berger Stigma Scale score and longitudinal change across the NIH Toolbox Cognition Battery measures. 89% of participants reported experiencing HIV stigma. In unadjusted analyses, greater HIV stigma was associated with worse attention performance at yearly follow-up visits (B = -0.07, 95% CI = -0.13 - -0.01, p = 0.025). When adjusting for clinicodemographic variables, HIV stigma was associated with worse processing speed and global cognition at yearly follow-up visits. This finding suggests that HIV stigma precedes subsequent cognitive decline and highlights the importance of reducing stigma to improve cognitive functioning among PWH.

Indexed as

CognitionCognitive DysfunctionHIV InfectionsSocial StigmaAdultCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsAttentionCognitionNeuropsychologyStigma

Identifiers

PMID39397137
PMCPMC11747836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.