Evidence map›Paper›PMID 39396998›Full record

ArticleBMC pediatrics2024

Residual transmission of HIV infection from mother to child in the Atlantic and littoral departments in Benin.

Edwige Hermione Dagba Gbessin, Haziz Sina, René Kpemahouton Keke, Michel Kiréopori Gomgnimbou, Aldric Afangnihoun, Moussa Bachabi, Abdoul-Salam Ouedraogo, Lamine Baba-Moussa

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Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Edwige Hermione Dagba GbessinNAZI BONI University, Bobo-Dioulasso, 01 BP 1091, Burkina Faso. Wendyshurst1@gmail.com.
Haziz SinaLaboratory of Biology and Molecular Typing in Microbiology (LBTMM), Faculty of Sciences and Technology (FAST), University of Abomey - Calavi, Cotonou, 05 BP 1604, Benin.
René Kpemahouton KekeNational Reference Laboratory of Health Program Fighting Against AIDS in Benin (NRL/PSLS), Health Ministry of Benin, Cotonou, Benin.
Michel Kiréopori GomgnimbouMolecular Biology Laboratory, Muraz Center, Higher Institute of Health Sciences (INSSA), Nazi Boni University, Bobo-Dioulasso, Burkina Faso.
Aldric AfangnihounHealth Program Fighting Against AIDS in Benin (PSLS), Health Ministry of Benin, Cotonou, Benin.
Moussa BachabiHealth Program Fighting Against AIDS in Benin (PSLS), Health Ministry of Benin, Cotonou, Benin.
Abdoul-Salam OuedraogoLaboratory of Emerging and Re-emerging Pathogens (LaPathER), Doctoral School of Health Sciences, Nazi BONI University, Bobo-Dioulasso, BP: 2161, Burkina Faso.
Lamine Baba-MoussaLaboratory of Biology and Molecular Typing in Microbiology (LBTMM), Faculty of Sciences and Technology (FAST), University of Abomey - Calavi, Cotonou, 05 BP 1604, Benin.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe implementation of the WHO's 2015 recommendations in Benin, requires an assessment of the progress made over time in preventing the transmission of the infection to exposed-infants, and the identification of its determinants.

methodsThis was a retrospective study of HIV-1 exposed-infants who underwent PCR between the 6

resultsA total of 5,312 infants benefited from early diagnosis by PCR between 2016 and 2021. Among them, 52% are males, tritherapy before pregnancy was the majority treatment used by mothers (30.6%) and monotherapy that of newborns (70%). Mixed breastfeeding is the feeding method with the highest prevalence. The overall transmission rate was 3.4% over the six years. The highest prevalence was achieved in 2018 (4.2%) and the lowest in 2021 (2.7%). The prevalence was lower when mothers were on tritherapy before pregnancy. The determinants of transmission were: mixed breastfeeding, lack of treatment in mothers (22.4%), lack of treatment in infants (19.7%), undefined treatments or absence of treatment in the mother-child pair.

conclusionThis study shows the contribution over time of the PMTCT program to reducing HIV transmission among exposed-infants and also underlines the need for proper conduct of treatment in any women of childbearing age.

Indexed as

HIV InfectionsInfectious Disease Transmission, VerticalBeninBreast FeedingFemaleHIV-1HumansInfantInfant, NewbornMalePregnancyPregnancy Complications, InfectiousPrevalenceRetrospective StudiesBenin – PMTCT – HIVEarly diagnosisTransmission rate

Identifiers

PMID39396998
PMCPMC11472565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.