Evidence map›Paper›PMID 39396883›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2025

Assessment of Obesity-related Metabolic Conditions: a novel objective scoring system better informs metabolic disease severity.

Victoria Lyo, John Arriola, Shushmita M Ahmed, Rouzbeh Mostaedi, Zainab Akinjobi, Hazem N Shamseddeen, Mohamed R Ali

Abstract read
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Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Victoria LyoDepartment of Surgery, University of California, Davis, California; Center for Alimentary and Metabolic Sciences, University of California, Davis, California.
John ArriolaDepartment of Surgery, University of California, Davis, California.
Shushmita M AhmedDepartment of Surgery, University of California, Davis, California; Center for Alimentary and Metabolic Sciences, University of California, Davis, California.
Rouzbeh MostaediKaiser Permanente, Richmond, California.
Zainab AkinjobiDepartment of Public Health Sciences, University of California, Davis, California.
Hazem N ShamseddeenDepartment of Surgery, University of California, Davis, California; Center for Alimentary and Metabolic Sciences, University of California, Davis, California.
Mohamed R AliDepartment of Surgery, University of California, Davis, California; Center for Alimentary and Metabolic Sciences, University of California, Davis, California. Electronic address: mrali@ucdavis.edu.

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Building Interdisciplinary Research Careers in Women's Health at UC DavisK12AR084220 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Nancy E Lane · 2023 to 2026
$3.0M
NCATS NIH HHS UL1 TR001860NIAMS NIH HHS K12 AR084220NICHD NIH HHS K12 HD051958
6 · The paper itself

Abstract

backgroundReporting of obesity-associated metabolic disease severity and longitudinal response to bariatric surgery is not standardized. We updated our co-morbidity scoring tool to the Assessment of Obesity-related Metabolic Conditions (AOMC) to combine pharmacotherapy and biochemical data to score diabetes mellitus (DM), hypertension (HTN), and dyslipidemia (DYS) severity.

objectivesThe aim of this study is to determine whether the AOMC system more accurately stages metabolic disease severity than a clinically based Assessment of Obesity-Related Comorbidities (AORC) system.

settingUniversity hospital, United States.

methodsA retrospective cohort study of prospectively collected demographic, clinical, and biochemical data was performed on adults evaluated for bariatric surgery over 6years. AORC versus AOMC scores and disease severity were compared using McNemar's and Wilcoxon's tests.

resultsOf 1442 patients, AOMC newly diagnosed metabolic disease in more patients than did AORC: DM (73.4% versus 44.5%), HTN (91.7% versus 67.9%), and DYS (63.8% versus 53.4%). Of those on pharmacotherapy, AOMC found fewer patients with adequately controlled disease: DM (39.9% versus 97.7%), HTN (64.7% versus 99.3%), and DYS (51.8% versus 99.0%). For those in whom both scores could be calculated, disease severity was upstaged in most patients: DM (65.9%), HTN (42.9%), and DYS (30.9%). There were also significant shifts toward higher scores for all conditions and severity classifications, with more patients diagnosed with pre-metabolic and severe disease (untreated/uncontrolled).

conclusionsOur study demonstrated that the severity of DM, HTN, and DYS is vastly under-represented by clinical history alone and lacks standardized assessments. Our AOMC tool more accurately describes longitudinal metabolic response to bariatric surgery.

Indexed as

Metabolic DiseasesObesityObesity, MorbidAdultBariatric SurgeryComorbidityDiabetes MellitusDyslipidemiasFemaleHumansHypertensionMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexDiabetesDyslipidemiaHypertensionMetabolic diseaseObjective assessmentResponse to bariatric surgery

Identifiers

PMID39396883
PMCPMC11805658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.