Evidence map›Paper›PMID 39396566›Full record

ArticleThe journal of pain2025

Transition from acute to chronic low back pain in a community-based cohort.

Colleen A Burke, Rebecca Fillipo, Steven Z George, Flavia P Kapos, Andrzej S Kosinski, Emily Ford, Stephanie T Danyluk, Carla A Kingsbury, Kelley Seebeck, Christopher E Lewis and 3 more

Abstract read
In one paragraph

Article in The journal of pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Colleen A BurkeDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University, Durham, NC, USA.
Rebecca FillipoDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University, Durham, NC, USA.
Steven Z GeorgeDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University, Durham, NC, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA.
Flavia P KaposDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University, Durham, NC, USA.
Andrzej S KosinskiDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Emily FordDuke Department of Medicine, Duke University, NC, USA; Duke Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC, USA.
Stephanie T DanylukDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Carla A KingsburyDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA; Duke Department of Medicine, Duke University, NC, USA.
Kelley SeebeckDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Christopher E LewisDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA; Duke Department of Medicine, Duke University, NC, USA.
Cecilia PlezDepartment of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA; Duke Department of Medicine, Duke University, NC, USA.
Michael C BrownDepartment of Neurosurgery, Duke University, Durham, NC, USA; Duke Cancer Institute, Duke University, Durham, NC, USA.
Adam P GoodeDepartment of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA; Department of Population Health Sciences, Duke University, Durham, NC, USA; Duke Clinical Research Institute, Duke University, Durham, NC, USA. Electronic address: adam.goode@duke.edu.

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Biomarkers to Advance Clinical Phenotypes of Low Back Pain (BACk)R01AR071440 · NIAMS · DUKE UNIVERSITY · PI Adam Goode · 2017 to 2026
$5.0M
Mechanical Biomarkers of Chronic Low Back PainR01AR075399 · NIAMS · DUKE UNIVERSITY · PI Louis E. DeFrate, Adam Goode · 2019 to 2026
$3.7M
Mentoring in Musculoskeletal Pain PhenotypesK24AR079594 · NIAMS · DUKE UNIVERSITY · PI Adam Goode · 2022 to 2026
$927k
Social Health Factors Associated with the Transition from Acute to Chronic Low Back PainF31AR084911 · NIAMS · DUKE UNIVERSITY · PI Colleen Burke · 2024 to 2026
$134k
NCATS NIH HHS UL1 TR002553NIAMS NIH HHS F31 AR084911NIAMS NIH HHS K24 AR079594NIAMS NIH HHS R01 AR071440NIAMS NIH HHS R01 AR075399
6 · The paper itself

Abstract

The transition from acute to chronic low back pain (LBP) in community settings is not well understood. The purpose of this study was to assess the feasibility of recruitment and estimate the transition and continuation of chronic LBP. We also explored characteristics associated with this transition to chronic LBP. We enrolled n = 131 participants, of which n = 118 (90 %) completed 3-month outcomes and n = 111 (85 %) completed 6-month outcomes. Acute LBP was defined by a duration of < 4 weeks and a 30-day LBP-free period before the current acute episode. Chronic LBP was defined as pain most or every day over the past 3 months. The transition from acute to chronic LBP at 3 months was 32.2 % (38/118), and at 6 months, 80.6 % (25/31) of participants who transitioned at 3 months continued to have chronic LBP at 6 months. Participants with more frequent acute LBP and at an intensity of 30/100 were more likely to transition to chronic LBP (Risk Ratio (RR)= 3.13, 95 % Confidence Interval (CI) 1.84, 5.30) and continue to have chronic LBP at 6-months (RR=3.10, 95 % CI 1.48, 6.08). Higher risk on the STarT Back Screening Tool was associated with the transition to chronic LBP at 3 months (RR=1.73, 95 % CI 1.28, 2.35) and continuation of chronic LBP at 6 months (RR=1.26, 95 % CI 1.10, 1.45). The recruitment of acute LBP was feasible in a community setting. Acute LBP is a common condition in the community and frequently transitions to chronic LBP, suggesting the potential for substantial burden in the community. PERSPECTIVE: This article presents the feasibility of conducting a community-based study to describe the transition, continuation, and psychosocial predictors of acute to chronic low back pain. These findings could help identify community participants at high risk of incident and continued chronic low back pain.

Indexed as

Acute PainChronic PainCommunity-Based Participatory ResearchDisease ProgressionLow Back PainPatient SelectionAdolescentAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedPain MeasurementTime FactorsAcute painChronic painCohort studyCommunity-based researchLow back pain

Identifiers

PMID39396566
PMCPMC11781977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.