ArticleScientific reports2024
Association between brain resting-state functional activities and migraine: a bidirectional mendelian randomization study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Genetic evidence for causal relationships between brain functional networks and domain-specific recovery after nondisabling ischemic stroke.Experimental biology and medicine (Maywood, N.J.) · 2026Article
- Abnormal intrinsic functional hubs and connectivity in nurses with occupational burnout: a resting-state fMRI study.Frontiers in public health · 2025Article
- A Bidirectional Mendelian Randomization Study of Causal Relationships Between Migraine and White-Matter Structural Connectivity.Journal of pain research · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
Researchers have conducted extensive research on the correlation between brain resting-state functional activities (RSFA) and migraine. However, we still do not fully understand the exact nature of the causal relationship between these RSFA and migraine. We conducted a bidirectional two-sample Mendelian randomization (MR) study to investigate the causal association between migraine and RSFA. We gathered summary statistics from genome-wide association studies for 191 resting-state functional magnetic resonance imaging phenotypes. We employed various analytical methods for bidirectional two-sample MR analyses. This included inverse variance weighted, weighted median, MR Egger, and the constrained maximum likelihood approaches. We also conducted pleiotropy and heterogeneity analyses to evaluate the robustness and reliability. We found the functional connectivity between the default mode and the central executive network (OR = 1.39, p = 4.77 × 10
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