ArticleBMC surgery2024
Analysis of the efficacy of Percutaneous Transhepatic Cholangiography Drainage (PTCD) and Endoscopic Retrograde Cholangiopancreatography (ERCP) in the treatment of Malignant Obstructive Jaundice (MOJ) in palliative drainage and preoperative biliary drainage: a single-center retrospective study.
Article in BMC surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Impact of acute cholangitis severity on the safety of laparoscopic common bile duct exploration with primary closure: a stratified retrospective study.Surgical endoscopy · 2026Article
- Impact of preoperative internal versus external biliary drainage on surgical and oncological outcomes after pancreaticoduodenectomy: a systematic review and meta-analysis.International journal of surgery (London, England) · 2026Article
- Article
- Endoscopic Retrograde Cholangiopancreatography Combined With Percutaneous Transhepatic Cholangial Drainage Sinus Tract for the Treatment of Giant Common Bile Duct Stones.ACG case reports journal · 2026Article
- Association of pre-drainage bilirubin levels and pathological features with survival in patients undergoing preoperative biliary drainage: a single-center retrospective study.Translational gastroenterology and hepatology · 2026Article
- A Technique to Improve the Success of Stent Placement for High-Level Malignant Biliary Obstruction Through PTCD Tract: A Case Report.Case reports in medicine · 2026Article
- Management and outcomes of patients with obstructive jaundice from pancreatobiliary diseases in Rwanda.BMC gastroenterology · 2025Article
- Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice.BMC surgery · 2025Article
- Enhancing palliative care in malignant obstructive jaundice: A critical care perspective on endoscopic biliary stenting.World journal of gastrointestinal surgery · 2025Article
- Mirizzi syndrome masquerading as gallbladder carcinoma: a case report on diagnostic challenges and multidisciplinary management.Frontiers in medicine · 2025Article
- Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice.Frontiers in medicine · 2025Article
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Authors and funding
8 authors.
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Abstract
purposeThis study aimed to assess the safety and efficacy of percutaneous transhepatic cholangiography drainage (PTCD) and endoscopic retrograde cholangiopancreatography (ERCP) in palliative drainage and preoperative biliary drainage for treating malignant obstructive jaundice (MOJ).
methodsA total of 520 patients with MOJ who underwent PTCD or ERCP were enrolled and classified into palliative drainage group and preoperative biliary drainage group. Baseline characteristics, liver function, blood routine, complications were compared among the groups.
resultsThe technical success rates for PTCD and ERCP in palliative group were 97.1% and 85.9%. In palliative drainage group, PTCD had higher levels of total bilirubin (TB) reduction (53.0 (30.0,97.0) vs. 36.8 (17.9,65.0), p < 0.001) and direct bilirubin (DB) reduction (42.0 (22.0,78.5) vs. 28.0 (12.0,50.8), p = 0.001) than ERCP. However, PTCD was associated with higher rates of drainage tube displacement (20 cases, 11.8%), while ERCP had a higher incidence of biliary infection (39 cases, 22.8%) and pancreatitis (7 cases, 4.1%). In preoperative drainage group, PTCD achieved a 50% reduction in total bilirubin faster than ERCP (7.1 days vs. 10.5 days). And the time from palliation of jaundice to surgery was 24.2 days in PTCD group and 35.7 days in ERCP group, a statistically significant difference (Student's t test, p = 0.017).
conclusionBoth PTCD and ERCP could improve liver function for MOJ patients. PTCD seems to offer better outcomes in jaundice reduction and liver function improvement in palliative drainage, but requires careful postoperative management. In preoperative biliary drainage, PTCD may be a better preoperative bridge to improve liver function and control infection.
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