Evidence map›Paper›PMID 39395927›Full record

ArticleDigestive diseases and sciences2024

Characteristics of Hospitalized Patients With and Without Celiac Disease on a Gluten-Free Diet.

Rachel Eklund, John W Blackett, Anne R Lee, Peter H R Green, Benjamin Lebwohl

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Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Rachel EklundCeliac Disease Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, Columbia University, New York, NY, USA.
John W BlackettCeliac Disease Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, Columbia University, New York, NY, USA.
Anne R LeeCeliac Disease Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, Columbia University, New York, NY, USA.
Peter H R GreenCeliac Disease Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, Columbia University, New York, NY, USA.
Benjamin LebwohlCeliac Disease Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, Columbia University, New York, NY, USA. BL114@cumc.columbia.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost people maintaining a gluten-free diet (GFD) do not have celiac disease (CD). Comorbidities and associated conditions in this population are largely unknown.

aimsThis study identified demographics, dietary patterns, and diagnoses for patients prescribed a GFD during hospitalization and compared patients with CD to those without CD.

methodsWe performed a retrospective cross-sectional study for hospital admissions with a GFD between Jan 1, 2010 and June 30, 2022, while excluding patients missing demographic data (n = 113). We compared patients with and without a CD diagnosis, including multivariable logistic regression to identify characteristics independently associated with a CD diagnosis.

resultsWe analyzed 1527 hospitalized patients of all ages. A minority (n = 467, 30.6%) carried a CD diagnosis. Age, sex, body mass index, and Medicare/Medicaid enrollment and additional diagnoses associated with a GFD (e.g., IBS) were not significantly different. The CD cohort was more predominantly white (66.6% vs 58.4%, p = 0.007) and non-Hispanic (62.5% vs. 52.7%, p = 0.001). While hospitalized, patients with CD had fewer additional dietary restrictions (mean 0.33 vs 0.56, p < 0.001) and more frequent micronutrient supplementation (26.6% vs 21.4%, p = 0.03). CD was independently associated with malnutrition (OR 1.86, 95% CI 1.31-2.65) and inversely associated with a vegetarian diet (OR 0.35, 95% CI 0.15-0.81), reduced lactose diet (OR 0.25, 95% CI 0.13-0.50), and Hispanic ethnicity (OR 0.56, 95% CI 0.35-0.90) while controlling for other covariates. DISCUSSION: Two-thirds of hospitalized patients receiving a GFD do not have a diagnosis of CD. Among GFD inpatients, CD is associated with fewer dietary restrictions and independently associated with malnutrition.

Indexed as

Celiac DiseaseDiet, Gluten-FreeHospitalizationAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultCeliac diseaseGluten-free dietMalnutrition

Identifiers

PMID39395927

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