Evidence map›Paper›PMID 39395800›Full record

ArticleThe Journal of biological chemistry2024

α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto tautomerization of oxaloacetate.

Yu Yang, Ian Davis, Ryan A Altman, Aimin Liu

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu YangState Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, China; Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA. Electronic address: yangyu@hubu.edu.cn.
Ian DavisDepartment of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA.
Ryan A AltmanBorch Department of Medicinal Chemistry and Molecular Pharmacology and Department of Chemistry, Purdue University, West Lafayette, Indiana, USA.
Aimin LiuDepartment of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA. Electronic address: Feradical@utsa.edu.

Funding

A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Aina E. Cohen, KEITH O HODGSON · 2020 to 2026
$43.3M
Protein-Derived Cofactor in Bifunctional Enzyme KatG from Mycobacterium tuberculosisR01GM152982 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI Aimin Liu · 2024 to 2026
$1.0M
Identification of CNS-Penetrant Tryptophan 2,3-Dioxygenase Degrading LigandsR21AG078775 · NIA · PURDUE UNIVERSITY · PI ALTMAN, RYAN A, LIU, AIMIN · 2022 to 2023
$421k
Targeting Tryptophan Dioxygenase Degradation for Suppression of Tumor Immune EvasionR21CA270879 · NCI · PURDUE UNIVERSITY · PI ALTMAN, RYAN A, LIU, AIMIN · 2022 to 2023
$390k
NCI NIH HHS R21 CA270879NIA NIH HHS R21 AG078775NIGMS NIH HHS P30 GM133894NIGMS NIH HHS R01 GM152982
6 · The paper itself

Abstract

ACMSD (α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase) is a key metalloenzyme critical for regulating de novo endogenous NAD

Indexed as

Carboxy-LyasesCatalytic DomainOxaloacetic AcidCatalysisCrystallography, X-RayHumansMalonatesMolecular Docking Simulationaminocarboxymuconate-semialdehyde decarboxylaseCarboxy-LyasesMalonatesmalonic acidOxaloacetic AciddecarboxylasekynureninemetalloenzymeNAD homeostasistryptophan metabolism

Identifiers

PMID39395800
PMCPMC11650718

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.