Evidence map›Paper›PMID 39395061›Full record

ArticleExperimental brain research2024

Assessing inter-ocular fixational eye movements throughout the lifespan.

Sophie C Yue, Gokce B Cakir, Aasef Shaikh, Fatema F Ghasia

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophie C YueCase Western University School of Medicine, Cleveland, OH, USA.
Gokce B CakirCole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.
Aasef ShaikhDepartment of Neurology, University Hospitals and Cleveland VA Medical Center, Cleveland, USA.
Fatema F GhasiaCole Eye Institute, Cleveland Clinic, Cleveland, OH, USA. ghasiaf@ccf.org.

Funding

Cleveland Eye Bank Foundation Cleveland Eye Bank FoundationClinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve UniversityLerner Research Institute, Cleveland Clinic Lerner Research Institute, Cleveland ClinicResearch to Prevent Blindness Research to Prevent BlindnessU.S. Department of Veterans Affairs U.S. Department of Veterans Affairs
6 · The paper itself

Abstract

This study aims to assess fixational eye movements (FEMs) obtained under binocular and monocular viewing in normal individuals across different age groups. We recruited 68 healthy participants divided into Group 1 (children, 3-9 years, n = 20), Group 2 (adolescents, 10-19 years, n = 26), and Group 3 (adults, 20-73 years, n = 22). FEMs were collected using a high-resolution video-based tracker under 3 viewing conditions: binocular viewing (BV), monocular viewing right eye (MV_RE), and monocular viewing left eye (MV_LE). We quantified fixation stability, the frequency, amplitude, and disconjugacy of fixational saccades, and inter-saccadic drift velocity in BV, MV_RE, and MV_LE. We also computed inter-ocular fixation stability under binocular viewing and monocular viewing in the 3 groups. Fixation instability (FI) and fixational saccade amplitudes were higher in Group 1 than in Group 3 whereas inter-saccadic drifts were increased in Group 3. Vergence stability was greater in binocular viewing than in monocular viewing likely due to binocular summation in all groups. However, the fixational saccade amplitude and drift velocity of the right and left eye did not significantly differ across different viewing conditions within each group. Interestingly, the inter-ocular fixation stability ratio and vergence stability showed no significant differences between the groups. In conclusion, FEMs differ across age groups but inter-ocular FEMs are immune to the effects of age and can be a valuable parameter while evaluating FEM abnormalities in diseases like amblyopia.

Indexed as

Fixation, OcularVision, BinocularAdolescentAdultAgedAgingChildChild, PreschoolFemaleHumansMaleMiddle AgedSaccadesVision, MonocularYoung AdultDevelopmentDriftFixational saccadesFixation stabilityVergence stability

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.