Evidence map›Paper›PMID 39394185›Full record

ArticleNature communications2024

Regional tuning of photoreceptor adaptation in the primate retina.

Aindrila Saha, Theodore Bucci, Jacob Baudin, Raunak Sinha

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Reversibly Desensitising the Human Retina to Delay Saccadic Reaction Time for Diagnostic Prototyping.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. High-Fidelity Backpropagation through Primate Foveal Cones.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Convergent re-evolution of CNS structures: focus on the fovea.Current opinion in genetics & development · 2026
    Review
  4. Article
  5. HIGH-FIDELITY BACKPROPAGATION THROUGH PRIMATE FOVEAL CONES.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aindrila SahaDepartment of Neuroscience, University of Wisconsin, Madison, WI, USA.ORCID 0000-0001-7666-3183
Theodore BucciDepartment of Neuroscience, University of Wisconsin, Madison, WI, USA.ORCID 0009-0007-1264-4654
Jacob BaudinDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA.
Raunak SinhaDepartment of Neuroscience, University of Wisconsin, Madison, WI, USA. raunak.sinha@wisc.edu.ORCID 0000-0002-7553-1274

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Regional differences in photoreceptor signalingR01EY031411 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Raunak Sinha · 2021 to 2026
$2.3M
NEI NIH HHS R01 EY031411NIH HHS P51 OD011106U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) EY031411
6 · The paper itself

Abstract

Adaptation in cone photoreceptors allows our visual system to effectively operate over an enormous range of light intensities. However, little is known about the properties of cone adaptation in the specialized region of the primate central retina called the fovea, which is densely packed with cones and mediates high-acuity central vision. Here we show that macaque foveal cones exhibit weaker and slower luminance adaptation compared to cones in the peripheral retina. We find that this difference in adaptive properties between foveal and peripheral cones is due to differences in the magnitude of a hyperpolarization-activated current, I

Indexed as

Fovea CentralisRetinaRetinal Cone Photoreceptor CellsAdaptation, OcularAnimalsMacaca mulattaMalePhotic Stimulation

Identifiers

PMID39394185
PMCPMC11470117

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.