Evidence map›Paper›PMID 39394088›Full record

ArticleBMC public health2024

Global, regional, and national impact of air pollution on stroke burden: changing landscape from 1990 to 2021.

Yu-Xiang Fan, Wen Zhang, Wei Li, Yong-Jie Ma, Hong-Qi Zhang

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  13. Echocardiographic predictors of futile recanalization in acute ischemic stroke.Revista da Associacao Medica Brasileira (1992) · 2025
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Xiang FanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Wen ZhangDepartment of Neurosurgery, Qingyang People's Hospital, Qingyang, 745000, China.
Wei LiDepartment of Neurosurgery, The People's Hospital of Leshan Central District, Leshan, 614000, China.
Yong-Jie MaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Hong-Qi ZhangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. xwzhanghq@163.com.

Funding

Capital Medical University Medical Innovation Ability Improvement Project 12300122National Natural Science Foundation of China 82220108010
6 · The paper itself

Abstract

backgroundExposure to air pollution contributes to cardiovascular disease-related deaths and morbidity, including stroke. However, few studies have examined the global stroke burden linked to air pollution. This study aimed to evaluate the global stroke morbidity and mortality associated with air pollution from 1990 to 2021.

methodWith the Global Burden of Disease Study (GBD) 2021, the numbers, and age-standardized rates (ASRs) of deaths and disability-adjusted life years (DALYs) for air pollution-related stroke were reported globally. Further subgroup analyses were conducted by age, sex, region and country, and stroke subtypes. A linear regression model explored global temporal trends and a cluster analysis examined temporal trends across GBD regions. To predict trends until 2040, the age-period-cohort (APC) model and the Bayesian age-period-cohort (BAPC) model were applied.

resultsIn 2021, there were 1,989,686 (95% uncertainty interval [95% UI], 1,530,479-2,493,238) deaths and 44,962,167 (95% UI, 35,020,339 - 55,467,024) DALYs due to air pollution-related stroke. The ASRs increased with age, peaking generally over 85 years. Males, the Central African region, and Guinea-Bissau showed higher stroke burdens Intracerebral hemorrhage was the most lethal subtype, with an ASR of 11.69 (95% UI 8.94-14.69) for deaths and 276.93 (95% UI 212.21-344.36) for DALYs. From 1990 to 2021, the crude number of deaths and DALYs increased by 13.4% and 6.3%, respectively, for the global stroke burden but showed a declining trend when age-standardized. Most GBD regions in Asia and Africa experienced an increasing stroke burden linked to air pollution, while Europe and America showed a decreasing trend. Predictions indicated a gradual reduction in ASRs, with higher rates in males from 2020 to 2040.

conclusionsThe global stroke burden associated with air pollution remained significant despite a decreasing trend until 2021. Although future predictions suggested a reduction, the crude counts for stroke burden remained substantial, with significant regional disparities. This warranted the implementation of public health policies and ongoing efforts.

Indexed as

Air PollutionGlobal HealthStrokeAdultAgedAged, 80 and overDisability-Adjusted Life YearsEnvironmental ExposureFemaleGlobal Burden of DiseaseHumansMaleMiddle AgedAir pollutionAPC modelGBD 2021GlobalStroke

Identifiers

PMID39394088
PMCPMC11470728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.