Evidence map›Paper›PMID 39394062›Full record

ArticleBMC cancer2024

Study of the significance of the combination of the fibrinogen-albumin ratio and sarcopenia in predicting the prognosis of laryngeal cancer patients undergoing radical surgery.

Yizheng Zhang, Zhiyong Meng, Ming Lu, Shenjiong Ruan, Jiao Zhou, Mingchen Zhang, Yanjun Huang, Kehui Chen, Xinyuan Luo, Cheng-Ke Xie and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yizheng Zhang *Department of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Zhiyong Meng *Department of Ophthalmology, Shaowu Municipal Hospital of Fujian Province, Shaowu, Nanping, Fujian, 354000, China.
Ming LuDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Shenjiong RuanDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Jiao ZhouDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Mingchen ZhangDepartment of Ophthalmology, Shaowu Municipal Hospital of Fujian Province, Shaowu, Nanping, Fujian, 354000, China.
Yanjun HuangDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Kehui ChenDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Xinyuan LuoDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China.
Cheng-Ke XieDepartment of Hepatobiliary Surgery, Fujian Provincial Hospital, Fuzhou, Fujian, 350045, China. 18559305202@163.com.
Chaohui ZhengDepartment of Otolaryngology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, 362000, China. zchfydfsey@163.com.

Funding

Medical Innovation Subject of Science and Technology Programme Project of Fujian Provincial Commission of Health Planning 2023CX01010037Quanzhou City High-level Talents Innovation and Entrepreneurship Project of Quanzhou Municipal Bureau of Science and Technology in 2022 2022C033Rthe Natural Fund of Nanping Municipal Government N2023J046the Provincial Natural Science Foundation of Fujian Provincial Department of Science and Technology 2023J01722
6 · The paper itself

Abstract

objectiveThis study aims to investigate how the impact of preoperative sarcopenia and inflammatory markers for laryngeal cancer patients and develop a new scoring system to predict their prognosis. MATERIALS AND

methodsPatients who underwent laryngectomy for laryngeal cancer (LC) from December 2015 to December 2020 at the Second Affiliated Hospital of Fujian Medical University were included. Independent prognostic factors were determined using univariate and multivariate analyses. A new scoring system (SFAR) was established based on FAR and preoperative sarcopenia, and statistically analyzed.

results198 cases included in this study that met the admission criteria. Multivariate analysis shown that preoperative sarcopenia, pTNM stage, and FAR were independent prognostic factors for laryngeal cancer. Based on these three indicators, we developed the SFAR scoring system. Multivariate analysis showed that SFAR was an independent predictor of laryngeal cancer (p < 0.001). SFAR was then incorporated into a prognostic model that included T-stage and N-stage, and a column-line graph was generated to accurately predict its survival.

conclusionSystemic inflammation and sarcopenia are significantly associated with postoperative prognosis in laryngeal cancer. A new scoring system (SFAR) had implications for improving the prognosis of patients undergoing surgery for laryngeal cancer.

Indexed as

FibrinogenLaryngeal NeoplasmsLaryngectomySarcopeniaAgedFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesSerum AlbuminFibrinogenSerum AlbuminFARLaryngeal cancerPreoperative sarcopeniaPrognosis

Identifiers

PMID39394062
PMCPMC11468157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.