Evidence map›Paper›PMID 39394059›Full record

ArticleBMC ophthalmology2024

Comprehensive analysis of strabismus reoperations: clinical insights and progression factors.

Rui Niu, Panpan Lv, Rui Hao, Wei Zhang

Registry-linked trialAbstract read
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07446621 (Risk Factors And Surgical Outcomes Of Strabismus Reoperation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07446621 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Risk Factors And Surgical Outcomes Of Strabismus Reoperation: A Clinical Study

TypeinterventionalSponsorAssiut UniversityRan2026 to 2027Enrolled62ConditionsStrabismus, Esotropia, ExotropiaArmsHorizontal Strabismus Reoperation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A differentiable simulation of the eye for patient-specific strabismus surgery planning.International journal of computer assisted radiology and surgery · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui Niu *Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
Panpan Lv *School of Medicine, Nankai University, Tianjin, China.
Rui HaoClinical College of Ophthalmology, Tianjin Medical University, Tianjin, China. haorui0311@126.com.
Wei ZhangClinical College of Ophthalmology, Tianjin Medical University, Tianjin, China. zhangwei_eye@163.com.

Funding

General Project of Tianjin Health Science and Technology Fund TJWJ2021MS041Tianjin Eye Hospital Science and Technology Fund Youth Cultivation Project YKPY2201Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK‑016A
6 · The paper itself

Abstract

backgroundTo compare and analyze clinical characteristics of patients undergoing two surgeries and multiple surgeries and explore relevant factors to lay the foundation for clinical prediction.

methodsA retrospective analysis was conducted on clinical data from all patients who underwent twice and multiple strabismus surgeries at Tianjin Eye Hospital between October 2012 and September 2021. Patients were divided into Group A (two surgeries) and Group B (more than two surgeries) based on the cumulative number of surgeries performed. Clinical details at the first recurrence, including sex, age, native place, overall medical history, onset time, visual acuity, affected muscle(s), etc., were documented. Non-parametric tests and chi-square tests were used to analyze clinical characteristics in each group. Binary and ordered logistic regression analysis assessed parameters associated with multiple reoperations. A linear mixed-term model observed factors impacting affected muscle(s) during surgery. Researchers examined clinical traits related to secondary strabismus variables.

resultsAmong the 910 included patients, 840 required two surgeries (Group A) and 70 underwent more than two surgeries (Group B). Significant differences were found in age, onset time, interval time, and secondary factors. Regression analysis highlighted the significant impact of interval time on the reoperation rate, effectively predicting outcomes in patients with concomitant strabismus. Other ophthalmoplegia and secondary factors significantly influenced reoperation rates in patients with non-concomitant strabismus. Interval time, esotropia, and exotropia were linked to concomitant secondary strabismus patients, while the number of surgeries, DVD, esotropia, exotropia, and esotropia V-pattern were associated with non-concomitant secondary strabismus patients. In a longitudinal study, patients with multiple surgeries showed a correlation between the vertical deviation angle magnitude and the number of involved extraocular muscles. Regression analysis revealed that in patients with concomitant strabismus, interval time, exotropia, and esotropia influenced the total number of muscles during surgery. For patients with non-concomitant strabismus, interval time, secondary factors, and SOP impacted the total number of muscles during surgery.

conclusionsInterval time in patients with concomitant strabismus, as well as secondary and other ophthalmoplegia in non-concomitant strabismus, are the main factors for multiple reoperations.

Indexed as

Oculomotor MusclesOphthalmologic Surgical ProceduresReoperationStrabismusVisual AcuityAdolescentAdultAgedChildChild, PreschoolDisease ProgressionFemaleFollow-Up StudiesHumansMaleMiddle AgedLogistic regression analysisReoperationStrabismusSurgery

Identifiers

PMID39394059
PMCPMC11468484

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.