Evidence map›Paper›PMID 39393830›Full record

ArticleAmerican journal of epidemiology2024

From Fetus to Eight: the CHILD Cohort Study.

Kozeta Miliku, Myrtha E Reyna, Maria Medeleanu, Ruixue Dai, Aimee Dubeau, Diana L Lefebvre, Kim Wright, Bassel Dawod, Marshall Beck, Elissa Brooks and 16 more

Abstract read
In one paragraph

Article in American journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Kozeta MilikuDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-9614-7191
Myrtha E ReynaDepartment of Pediatrics and Translational Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Maria MedeleanuDepartment of Pediatrics and Translational Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Ruixue DaiDepartment of Pediatrics and Translational Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Aimee DubeauDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Diana L LefebvreDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Kim WrightDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Bassel DawodDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Marshall BeckDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Elissa BrooksDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Michael KoborDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Qingling DuanDepartment of Biomedical and Molecular Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Jeffrey R BrookDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Wendy LouDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Fiona S L BrinkmanDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
Geoffrey L WinsorDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
Justin CookDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
Allan B BeckerDepartment of Pediatrics and Child Health, Randy Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Elinor SimonsDepartment of Pediatrics and Child Health, Randy Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Piushkumar J MandhaneDepartment of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Canada.
Theo J MoraesDepartment of Pediatrics and Translational Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Meghan B AzadDepartment of Pediatrics and Child Health, Randy Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Malcolm R SearsDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Stuart E TurveyDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Padmaja SubbaraoDepartment of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
CHILD Study Investigators

Funding

Allergy, Genes and Environment (AllerGen) Network of Centres of Excellence (NCE)BC Children's Hospital FoundationCIHRCompute CanadaDon & Debbie Morrison,Genome AlbertaGenome British ColumbiaGenome CanadaOntario Research FundProvincial Health Services AuthoritySchroeder Foundation,Sick Kids Hospital FoundationSimon Fraser UniversityWomen and Children's Health Research Institute
6 · The paper itself

Abstract

The CHILD Cohort Study is an active multi-center longitudinal, prospective, population pregnancy cohort study following Canadian infants from fetal life until adulthood. We hypothesized that early life physical and psychosocial environments interact with biological factors (e.g. immunologic, genetic, physiologic, and metabolic) influencing burdensome non-communicable disease outcomes, including asthma and allergic disorders, growth and development, cardio-metabolic health, and neurodevelopmental outcomes that manifest during the life-course. Detailed clinical and physiologic phenotyping at strategic intervals was complemented by environmental sampling, actigraphy and global positioning system measures, biological sampling including gut, breastmilk and nasal microbiome, nutritional studies, genetics, and epigenetic profiling. Of 3,454 families recruited from 2008 to 2012, study retention was 96.0% at 1-year, 93.2% at 5-years and 90.7% at 8-years. Data collection during the SARS-2 COVID-19 pandemic was partially completed via virtual visits. A sub-cohort was implemented, capturing detailed information on the prevalence and predictors of SARS-CoV-2 infection and the health and psychosocial impact of the pandemic on Canadian families. The 13-year clinical assessment launched in 2022 will be completed in 2025. Ultimately, the CHILD Cohort Study provides a data science platform designed to enable a deep understanding of early life factors associated with the development of chronic non-communicable diseases and multimorbidity.

Indexed as

allergiesasthmacardiovascular healthCHILD cohort studydata science platformenvironmentgenesgrowth trajectorieslongitudinal prospective population-based studymental healthmicrobiomenormative cohortobesitypediatrics

Identifiers

PMID39393830
PMCPMC12234225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.